Publikation

Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial.

Wissenschaftlicher Artikel/Review - 23.03.2021

Bereiche
PubMed
DOI
Kontakt

Zitation
Engelter S, Traenka C, Gensicke H, Schaedelin S, Luft A, Simonetti B, Fischer U, Michel P, Sirimarco G, Kägi G, Vehoff J, Nedeltchev K, Kahles T, Kellert L, Rosenbaum S, von Rennenberg R, Sztajzel R, Leib S, Jung S, Gralla J, Bruni N, Seiffge D, Feil K, Polymeris A, Steiner L, Hamann J, Bonati L, Brehm A, De Marchis G, Peters N, Stippich C, Nolte C, Christensen H, Wegener S, Psychogios M, Arnold M, Lyrer P, TREAT-CAD investigators. Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial. Lancet Neurol 2021; 20:341-350.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Lancet Neurol 2021; 20
Veröffentlichungsdatum
23.03.2021
eISSN (Online)
1474-4465
Seiten
341-350
Kurzbeschreibung/Zielsetzung

Cervical artery dissection is a major cause of stroke in young people (aged <50 years). Historically, clinicians have preferred using oral anticoagulation with vitamin K antagonists for patients with cervical artery dissection, although some current guidelines-based on available evidence from mostly observational studies-suggest using aspirin. If proven to be non-inferior to vitamin K antagonists, aspirin might be preferable, due to its ease of use and lower cost. We aimed to test the non-inferiority of aspirin to vitamin K antagonists in patients with cervical artery dissection.