Publikation
Update Breast Cancer 2020 Part 3 - Early Breast Cancer
Wissenschaftlicher Artikel/Review - 06.11.2020
Huober Jens, Schütz Florian, Luftner Diana, Fehm Tanja N, Tesch Hans, Overkamp Friedrich, Welslau Manfred, Schulmeyer Carla E, Kolberg Hans-Christian, Fasching Peter A, Thill Marc, Belleville Erik, Ettl Johannes, Janni Wolfgang, Lux Michael P, Müller Volkmar, Hartkopf Andreas D, Schneeweiss Andreas, Wöckel Achim
Bereiche
PubMed
DOI
Zitation
Art
Zeitschrift
Veröffentlichungsdatum
ISSN (Druck)
Seiten
Kurzbeschreibung/Zielsetzung
The treatment of patients with early breast cancer has always been characterised by escalation by new therapies and de-escalation through identification of better treatment regimens or introduction of better tools to estimate prognosis. Efforts in some of these areas in the last few years have led to solid data. The results of the large studies of de-escalation through use of multi-gene tests are available, as are the results of some studies that investigated the new anti-HER2 substances T-DM1 and pertuzumab in the early treatment situation. Several large-scale studies examining the role of CDK4/6 inhibitors will soon be concluded so innovations can be anticipated in this area also. This review article will summarise and classify the results of the latest publications.