Projekt

Exploring the impact of hexagonal boron nitride (nanomedicines) on bacterial quorum sensing communication and its consequences on bacterial lung invasionand pathogenesis

Geplant · 2023 bis 2024

Art
Grundlagenforschung
Status
Geplant
Start
2023
Ende
2024
Finanzierungsart
Fördermittel KSSG
Projektpartner
Empa: Dr. Tina Bürki, Group leader Particles@Barriers, Empa and Dr. Govind Gupta, scientist Particles@Barriers, Empa
Kurzbeschreibung/Zielsetzung

In this interdisciplinary collaboration between Empa's Laboratory for Particles-Biology Interactions (Particles@Barriers subgroup) and the KSSG (Infektiologie/Spitalhygiene), we aim to study whether hexagonal boron nitride (hBN) could modulate host-invasion, virulence, and pathogenesis of Streptococcus pneumoniae by affecting luxP/luxS mediated quorum sensing signaling.