Andreas Bergthaler
A replicating LCMV-based vaccine for the treatment of solid tumors.
Purde M, Cupovic J, Palmowski Y, Makky A, Schmidt S, Rochwarger A, Hartmann F, Stemeseder F, Lercher A, Abdou M, Bomze D, Besse L, Berner F, Tüting T, Hölzel M, Bergthaler A, Kochanek S, Ludewig B, Lauterbach H, Orlinger K, Bald T, Schietinger A, Schürch C, Ring S, Flatz L. A replicating LCMV-based vaccine for the treatment of solid tumors. Mol Ther 2023
05.12.2023A replicating LCMV-based vaccine for the treatment of solid tumors.
05.12.2023Mol Ther 2023
Purde Mette-Triin, Cupovic Jovana, Palmowski Yannick A, Makky Ahmad, Schmidt Sarah, Rochwarger Alexander, Hartmann Fabienne, Stemeseder Felix, Lercher Alexander, Abdou Marie-Therese, Bomze David, Besse Lenka, Berner Fiamma, Tüting Thomas, Hölzel Michael, Bergthaler Andreas, Kochanek Stefan, Ludewig Burkhard, Lauterbach Henning, Orlinger Klaus K, Bald Tobias, Schietinger Andrea, Schürch Christian M, Ring Sandra Stephanie, Flatz Lukas
Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients.
Lichtensteiger C, Koblischke M, Berner F, Jochum A, Sinnberg T, Balciunaite B, Purde M, Walter V, Abdou M, Hofmeister K, Kohler P, Vernazza P, Albrich W, Kahlert C, Zoufaly A, Traugott M, Kern L, Pietsch U, Kleger G, Filipovic M, Kneilling M, Cozzio A, Pop O, Bomze D, Bergthaler A, Hasan A, Aberle J, Flatz L. Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients. J Autoimmun 2023; 140:103118.
10.10.2023Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients.
10.10.2023J Autoimmun 2023; 140:103118
Lichtensteiger Christa, Koblischke Maximilian, Berner Fiamma, Jochum Ann-Kristin, Sinnberg Tobias, Balciunaite Beatrice, Purde Mette-Triin, Walter Vincent, Abdou Marie-Therese, Hofmeister Kathrin, Kohler Philipp, Vernazza Pietro L, Albrich Werner, Kahlert Christian, Zoufaly Alexander, Traugott Marianna T, Kern Lukas, Pietsch Urs, Kleger Gian-Reto, Filipovic Miodrag, Kneilling Manfred, Cozzio Antonio, Pop Oltin, Bomze David, Bergthaler Andreas, Hasan Ali, Aberle Judith, Flatz Lukas
Erratum to: Severe Coronavirus Disease 2019 (COVID-19) is Associated With Elevated Serum Immunoglobulin (Ig) A and Antiphospholipid IgA Antibodies.
Hasan Ali O, Bomze D, Risch L, Brugger S, Paprotny M, Weber M, Thiel S, Kern L, Albrich W, Kohler P, Kahlert C, Vernazza P, Bühler P, Schüpbach R, Gómez-Mejia A, Popa A, Bergthaler A, Penninger J, Flatz L. Erratum to: Severe Coronavirus Disease 2019 (COVID-19) is Associated With Elevated Serum Immunoglobulin (Ig) A and Antiphospholipid IgA Antibodies. Clin Infect Dis 2021; 73:1746.
02.11.2021Erratum to: Severe Coronavirus Disease 2019 (COVID-19) is Associated With Elevated Serum Immunoglobulin (Ig) A and Antiphospholipid IgA Antibodies.
02.11.2021Clin Infect Dis 2021; 73:1746
Hasan Ali Omar, Bomze David, Risch Lorenz, Brugger Silvio D, Paprotny Matthias, Weber Myriam, Thiel Sarah, Kern Lukas, Albrich Werner, Kohler Philipp, Kahlert Christian, Vernazza Pietro, Bühler Philipp K, Schüpbach Reto A, Gómez-Mejia Alejandro, Popa Alexandra M, Bergthaler Andreas, Penninger Josef M, Flatz Lukas
Severe Coronavirus Disease 2019 (COVID-19) is Associated With Elevated Serum Immunoglobulin (Ig) A and Antiphospholipid IgA Antibodies
Hasan Ali O, Penninger J, Bergthaler A, Popa A, Gómez-Mejia A, Schüpbach R, Bühler P, Vernazza P, Kahlert C, Kohler P, Albrich W, Kern L, Thiel S, Weber M, Paprotny M, Brugger S, Risch L, Bomze D, Flatz L. Severe Coronavirus Disease 2019 (COVID-19) is Associated With Elevated Serum Immunoglobulin (Ig) A and Antiphospholipid IgA Antibodies. Clin Infect Dis 2021; 73:e2869-e2874.
02.01.2021Severe Coronavirus Disease 2019 (COVID-19) is Associated With Elevated Serum Immunoglobulin (Ig) A and Antiphospholipid IgA Antibodies
02.01.2021Clin Infect Dis 2021; 73:e2869-e2874
Hasan Ali Omar, Penninger Josef M, Bergthaler Andreas, Popa Alexandra M, Gómez-Mejia Alejandro, Schüpbach Reto A, Bühler Philipp K, Vernazza Pietro, Kahlert Christian, Kohler Philipp, Albrich Werner, Kern Lukas, Thiel Sarah, Weber Myriam, Paprotny Matthias, Brugger Silvio D, Risch Lorenz, Bomze David, Flatz Lukas
Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function
Lercher A, Pikor N, Reil D, Ozsvár-Kozma M, Kalinke U, Ludewig B, Moriggl R, Bennett K, Menche J, Cheng P, Schabbauer G, Trauner M, Klavins K, Orlova A, Genger J, Bhattacharya A, Popa A, Caldera M, Schlapansky M, Baazim H, Agerer B, Gürtl B, Kosack L, Májek P, Brunner J, Vitko D, Pinter T, Bergthaler A. Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function. Immunity 2019; 51:1074-1087.e9.
26.11.2019Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function
26.11.2019Immunity 2019; 51:1074-1087.e9
Lercher Alexander, Pikor Natalia, Reil Daniela, Ozsvár-Kozma Maria, Kalinke Ulrich, Ludewig Burkhard, Moriggl Richard, Bennett Keiryn L, Menche Jörg, Cheng Paul N, Schabbauer Gernot, Trauner Michael, Klavins Kristaps, Orlova Anna, Genger Jakob-Wendelin, Bhattacharya Anannya, Popa Alexandra M, Caldera Michael, Schlapansky Moritz F, Baazim Hatoon, Agerer Benedikt, Gürtl Bettina, Kosack Lindsay, Májek Peter, Brunner Julia S, Vitko Dijana, Pinter Theresa, Bergthaler Andreas
Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection
Sommerstein R, Siegrist C, Lambert P, Bowden T, Coutard B, Rabah N, Meda P, Rigo D, Ter Meulen J, Igonet S, Bergthaler A, Sahin M, Fischer N, Magistrelli G, Malinge P, Remy M, Flatz L, Pinschewer D. Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection. PLoS Pathog 2015; 11:e1005276.
20.11.2015Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection
20.11.2015PLoS Pathog 2015; 11:e1005276
Sommerstein Rami, Siegrist Claire-Anne, Lambert Paul-Henri, Bowden Thomas A, Coutard Bruno, Rabah Nadia, Meda Paolo, Rigo Dorothée, Ter Meulen Jan, Igonet Sebastien, Bergthaler Andreas, Sahin Mehmet, Fischer Nicolas, Magistrelli Giovanni, Malinge Pauline, Remy Melissa M, Flatz Lukas, Pinschewer Daniel D
Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage
Bhattacharya A, Arnold I, Flatz L, Xu H, Lang P, Aderem A, Takaoka A, Superti-Furga G, Colinge J, Ludewig B, Löhning M, Baazim H, Khamina K, Panse I, Hegazy A, Deigendesch N, Kosack L, Cupovic J, Kandasamy R, Hildebrandt A, Merkler D, Kühl A, Vilagos B, Schliehe C, Bergthaler A. Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage. Immunity 2015; 43:974-86.
17.11.2015Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage
17.11.2015Immunity 2015; 43:974-86
Bhattacharya Anannya, Arnold Isabelle, Flatz Lukas, Xu Haifeng C, Lang Philipp A, Aderem Alan, Takaoka Akinori, Superti-Furga Giulio, Colinge Jacques, Ludewig Burkhard, Löhning Max, Baazim Hatoon, Khamina Kseniya, Panse Isabel, Hegazy Ahmed N, Deigendesch Nikolaus, Kosack Lindsay, Cupovic Jovana, Kandasamy Richard K, Hildebrandt Andrea, Merkler Doron, Kühl Anja A, Vilagos Bojan, Schliehe Christopher, Bergthaler Andreas
Protective efficacy of individual CD8+ T cell specificities in chronic viral infection
Johnson S, Bergthaler A, Graw F, Flatz L, Bonilla W, Siegrist C, Lambert P, Regoes R, Pinschewer D. Protective efficacy of individual CD8+ T cell specificities in chronic viral infection. J Immunol 2015; 194:1755-62.
07.01.2015Protective efficacy of individual CD8+ T cell specificities in chronic viral infection
07.01.2015J Immunol 2015; 194:1755-62
Johnson Susan, Bergthaler Andreas, Graw Frederik, Flatz Lukas, Bonilla Weldy V, Siegrist Claire-Anne, Lambert Paul-Henri, Regoes Roland R, Pinschewer Daniel D
Evolution of Recombinant Lymphocytic Choriomeningitis Virus/Lassa Virus In Vivo Highlights the Importance of the GPC Cytosolic Tail in Viral Fitness
Sommerstein R, Ramos da Palma J, Olschläger S, Bergthaler A, Barba L, Lee B, Pasquato A, Flatz L. Evolution of Recombinant Lymphocytic Choriomeningitis Virus/Lassa Virus In Vivo Highlights the Importance of the GPC Cytosolic Tail in Viral Fitness. J Virol 2014; 88:8340-8348.
14.05.2014Evolution of Recombinant Lymphocytic Choriomeningitis Virus/Lassa Virus In Vivo Highlights the Importance of the GPC Cytosolic Tail in Viral Fitness
14.05.2014J Virol 2014; 88:8340-8348
Sommerstein Rami, Ramos da Palma Joel, Olschläger Stephan, Bergthaler Andreas, Barba Leticia, Lee Boris P-L, Pasquato Antonella, Flatz Lukas
Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression
Bergthaler A, Flatz L, Hegazy A, Johnson S, Horvath E, Löhning M, Pinschewer D. Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression. Proc Natl Acad Sci USA 2010; 107:21641-6.
22.11.2010Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression
22.11.2010Proc Natl Acad Sci USA 2010; 107:21641-6
Bergthaler Andreas, Flatz Lukas, Hegazy Ahmed N, Johnson Susan, Horvath Edit, Löhning Max, Pinschewer Daniel D
Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes
Pinschewer D, Flatz L, Steinborn R, Horvath E, Fernandez M, Lutz H, Suter M, Bergthaler A. Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes. Int Immunol 2010; 22:749-56.
28.06.2010Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes
28.06.2010Int Immunol 2010; 22:749-56
Pinschewer Daniel D, Flatz Lukas, Steinborn Ralf, Horvath Edit, Fernandez Marylise, Lutz Hans, Suter Mark, Bergthaler Andreas
T cell-dependence of Lassa fever pathogenesis
Flatz L, Günther S, Hanisch U, Brück W, Kreutzfeldt M, Verschoor A, Bestmann L, Schedensack M, Regen T, Bergthaler A, Merkler D, Rieger T, Pinschewer D. T cell-dependence of Lassa fever pathogenesis. PLoS Pathog 2010; 6:e1000836.
26.03.2010T cell-dependence of Lassa fever pathogenesis
26.03.2010PLoS Pathog 2010; 6:e1000836
Flatz Lukas, Günther Stephan, Hanisch Uwe-Karsten, Brück Wolfgang, Kreutzfeldt Mario, Verschoor Admar, Bestmann Lukas, Schedensack Mariann, Regen Tommy, Bergthaler Andreas, Merkler Doron, Rieger Toni, Pinschewer Daniel D
Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity
Flatz L, Radbruch A, Levy F, Lambert P, Siegrist C, Restifo N, Löhning M, Ochsenbein A, Nabel G, Broek M, Kochanek S, Hegazy A, Bergthaler A, Verschoor A, Claus C, Fernandez M, Gattinoni L, Johnson S, Kreppel F, Pinschewer D. Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity. Nat Med 2010; 16:339-45.
07.02.2010Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity
07.02.2010Nat Med 2010; 16:339-45
Flatz Lukas, Radbruch Andreas, Levy Frederic, Lambert Paul-Henri, Siegrist Claire-Anne, Restifo Nicholas P, Löhning Max, Ochsenbein Adrian F, Nabel Gary J, Broek Maries van den, Kochanek Stefan, Hegazy Ahmed N, Bergthaler Andreas, Verschoor Admar, Claus Christina, Fernandez Marylise, Gattinoni Luca, Johnson Susan, Kreppel Florian, Pinschewer Daniel D
Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions
Hegazy A, Radbruch A, Pinschewer D, Flatz L, Bergthaler A, Fröhlich A, Panse I, Helmstetter C, Peine M, Löhning M. Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions. Immunity 2010; 32:116-28.
14.01.2010Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions
14.01.2010Immunity 2010; 32:116-28
Hegazy Ahmed N, Radbruch Andreas, Pinschewer Daniel D, Flatz Lukas, Bergthaler Andreas, Fröhlich Anja, Panse Isabel, Helmstetter Caroline, Peine Michael, Löhning Max
Impaired antibody response causes persistence of prototypic T cell-contained virus
Bergthaler A, Siegrist C, Odermatt B, Verbeek J, Senn B, Fitsche A, Fernandez M, Horvath E, Sommerstein R, Merkler D, Eschli B, Fink K, Holdener M, Hegazy A, Verschoor A, Flatz L, Pinschewer D. Impaired antibody response causes persistence of prototypic T cell-contained virus. PLoS Biol 2009; 7:e1000080.
07.04.2009Impaired antibody response causes persistence of prototypic T cell-contained virus
07.04.2009PLoS Biol 2009; 7:e1000080
Bergthaler Andreas, Siegrist Claire-Anne, Odermatt Bernhard, Verbeek J Sjef, Senn Beatrice M, Fitsche André, Fernandez Marylise, Horvath Edit, Sommerstein Rami, Merkler Doron, Eschli Bruno, Fink Katja, Holdener Martin, Hegazy Ahmed N, Verschoor Admar, Flatz Lukas, Pinschewer Daniel D
Hematopoietic cell-derived interferon controls viral replication and virus-induced disease
Lang P, Ohashi P, Ludewig B, Honda K, Bergthaler A, Flatz L, Pellegrini M, Recher M, Navarini A, Verschoor A, Cervantes-Barragan L, Lang K. Hematopoietic cell-derived interferon controls viral replication and virus-induced disease. Blood 2009; 113:1045-52.
29.01.2009Hematopoietic cell-derived interferon controls viral replication and virus-induced disease
29.01.2009Blood 2009; 113:1045-52
Lang Philipp A, Ohashi Pamela S, Ludewig Burkhard, Honda Kenya, Bergthaler Andreas, Flatz Lukas, Pellegrini Marc, Recher Mike, Navarini Alexander A, Verschoor Admar, Cervantes-Barragan Luisa, Lang Karl S
Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses
Navarini A, Hengartner H, Odermatt B, Landmann R, Bille J, Flatz L, Bergthaler A, Meury S, Georgiev P, Lang K, Recher M, Zinkernagel R. Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses. Proc Natl Acad Sci USA 2006; 103:15535-9.
09.10.2006Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses
09.10.2006Proc Natl Acad Sci USA 2006; 103:15535-9
Navarini Alexander A, Hengartner Hans, Odermatt Bernhard, Landmann Regine, Bille Jacques, Flatz Lukas, Bergthaler Andreas, Meury Susanne, Georgiev Panco, Lang Karl S, Recher Mike, Zinkernagel Rolf M
Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA
Flatz L, Bergthaler A, de la Torre J, Pinschewer D. Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA. Proc Natl Acad Sci USA 2006; 103:4663-8.
13.03.2006Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA
13.03.2006Proc Natl Acad Sci USA 2006; 103:4663-8
Flatz Lukas, Bergthaler Andreas, de la Torre Juan Carlos, Pinschewer Daniel D