Mechthild Lütge
Deciphering the molecular landscape of the stromal cells in human lymph nodes at the single-cell level
01.09.2019
Grundlagenforschung - 01.09.2019 - 31.03.2025
Laufend
Projektleitung: Ludewig Burkhard
Mitarbeiter/innen: Stanossek Yves, Meili Samuel, De Martin Angelina, Lütge Mechthild, Kurz Lisa, Cheng Hung-Wei
Stromal Cell Niches at the Nexus of the Innate Lymphoid Cell Interactome
01.01.2019Innate lymphoid cells (ILCs) critically impact a diverse array of diseases. While the main cell-intrinsic molecular pathways and some of the soluble mediators that regulate ILC development and their functional activity have been characterized, the ce...
Grundlagenforschung - 01.01.2019 - 31.12.2022
Automatisch geschlossen
Projektleitung: Ludewig Burkhard
Mitarbeiter/innen: Lütge Mechthild
Deciphering the transcriptomic landscape of cancer-associated fibroblasts in pancreatic cancer / Oncological Research
01.01.2019Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancer types with a 5-year survival of only 7% and strongly limited treatment options. A major obstacle for successful treatment is the immunosuppressive nature of the tumor microe...
Grundlagenforschung - 01.01.2019 - 31.12.2021
Automatisch geschlossen
Projektleitung: Ludewig Burkhard, Lütge Mechthild
Deciphering the transcriptomic landscape of cancer-associated fibroblasts in pancreatic cancer – an exploratory clinical study
01.07.2018Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancer types with a 5-year survival of only 7% 1. While surgical resection of localized disease offers a moderate increase in survival, patients with metastatic pancreas cancer are...
Grundlagenforschung - 01.07.2018 - 31.12.2018
Abgeschlossen
Projektleitung: Ludewig Burkhard
Mitarbeiter/innen: Lütge Mechthild