Alwin D R Huitema
Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol.
Mc Laughlin A, Schmulenson E, Teplytska O, Zimmermann S, Opitz P, Groenland S, Huitema A, Steeghs N, Müller L, Fuxius S, Illerhaus G, Jörger M, Mayer F, Fuhr U, Holdenrieder S, Hempel G, Scherf-Clavel O, Jaehde U, Kloft C, For The On-Target Study Consortium. Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol. Cancers (Basel) 2021; 13
14.12.2021Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol.
14.12.2021Cancers (Basel) 2021; 13
Mc Laughlin Anna M, Schmulenson Eduard, Teplytska Olga, Zimmermann Sebastian, Opitz Patrick, Groenland Stefanie L, Huitema Alwin D R, Steeghs Neeltje, Müller Lothar, Fuxius Stefan, Illerhaus Gerald, Jörger Markus, Mayer Frank, Fuhr Uwe, Holdenrieder Stefan, Hempel Georg, Scherf-Clavel Oliver, Jaehde Ulrich, Kloft Charlotte, For The On-Target Study Consortium
Precision Dosing of Targeted Therapies Is Ready for Prime Time
Groenland S, Verheijen R, Jörger M, Mathijssen R, Sparreboom A, Beijnen J, Beumer J, Steeghs N, Huitema A. Precision Dosing of Targeted Therapies Is Ready for Prime Time. Clin Cancer Res 2021; 27:6644-6652.
21.09.2021Precision Dosing of Targeted Therapies Is Ready for Prime Time
21.09.2021Clin Cancer Res 2021; 27:6644-6652
Groenland Stefanie L, Verheijen Remy B, Jörger Markus, Mathijssen Ron H J, Sparreboom Alex, Beijnen Jos H, Beumer Jan H, Steeghs Neeltje, Huitema Alwin D R
Pharmacokinetics of Capecitabine and Four Metabolites in a Heterogeneous Population of Cancer Patients: A Comprehensive Analysis.
Jacobs B, Deenen M, Joerger M, Rosing H, de Vries N, Meulendijks D, Cats A, Beijnen J, Schellens J, Huitema A. Pharmacokinetics of Capecitabine and Four Metabolites in a Heterogeneous Population of Cancer Patients: A Comprehensive Analysis. CPT Pharmacometrics Syst Pharmacol 2019; 8:940-950.
20.11.2019Pharmacokinetics of Capecitabine and Four Metabolites in a Heterogeneous Population of Cancer Patients: A Comprehensive Analysis.
20.11.2019CPT Pharmacometrics Syst Pharmacol 2019; 8:940-950
Jacobs Bart A W, Deenen Maarten J, Joerger Markus, Rosing Hilde, de Vries Niels, Meulendijks Didier, Cats Annemieke, Beijnen Jos H, Schellens Jan H M, Huitema Alwin D R
Does Older Age Lead to Higher Risk for Neutropenia in Patients Treated with Paclitaxel?
Crombag M, Koolen S, Wijngaard S, Jörger M, Dorlo T, van Erp N, Mathijssen R, Beijnen J, Huitema A. Does Older Age Lead to Higher Risk for Neutropenia in Patients Treated with Paclitaxel?. Pharm Res 2019; 36:163.
15.10.2019Does Older Age Lead to Higher Risk for Neutropenia in Patients Treated with Paclitaxel?
15.10.2019Pharm Res 2019; 36:163
Crombag Marie-Rose B S, Koolen Stijn L W, Wijngaard Sophie, Jörger Markus, Dorlo Thomas P C, van Erp Nielka P, Mathijssen Ron H J, Beijnen Jos H, Huitema Alwin D R
Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study
Crombag M, Beijnen J, Mathijssen R, van Erp N, Dorlo T, Schellens J, Jörger M, Wijngaard S, Koolen S, de Vries Schultink A, Huitema A. Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study. Pharm Res 2019; 36:33.
07.01.2019Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study
07.01.2019Pharm Res 2019; 36:33
Crombag Marie-Rose B S, Beijnen Jos H, Mathijssen Ron H J, van Erp Nielka P, Dorlo Thomas P C, Schellens Jan H M, Jörger Markus, Wijngaard Sophie, Koolen Stijn L W, de Vries Schultink Aurelia H M, Huitema Alwin D R
Pharmacokinetics of Selected Anticancer Drugs in Elderly Cancer Patients: Focus on Breast Cancer
Crombag M, Jörger M, Thürlimann B, Schellens J, Beijnen J, Huitema A. Pharmacokinetics of Selected Anticancer Drugs in Elderly Cancer Patients: Focus on Breast Cancer. Cancers (Basel) 2016; 8
02.01.2016Pharmacokinetics of Selected Anticancer Drugs in Elderly Cancer Patients: Focus on Breast Cancer
02.01.2016Cancers (Basel) 2016; 8
Crombag Marie-Rose B S, Jörger Markus, Thürlimann Beat, Schellens Jan H M, Beijnen Jos H, Huitema Alwin D R
Evaluation of a pharmacology-driven dosing algorithm of 3-weekly paclitaxel using therapeutic drug monitoring: a pharmacokinetic-pharmacodynamic simulation study
Jörger M, Kraff S, Huitema A, Feiss G, Moritz B, Schellens J, Beijnen J, Jaehde U. Evaluation of a pharmacology-driven dosing algorithm of 3-weekly paclitaxel using therapeutic drug monitoring: a pharmacokinetic-pharmacodynamic simulation study. Clin Pharmacokinet 2012; 51:607-17.
01.09.2012Evaluation of a pharmacology-driven dosing algorithm of 3-weekly paclitaxel using therapeutic drug monitoring: a pharmacokinetic-pharmacodynamic simulation study
01.09.2012Clin Pharmacokinet 2012; 51:607-17
Jörger Markus, Kraff Stefanie, Huitema Alwin D R, Feiss Gary, Moritz Berta, Schellens Jan H M, Beijnen Jos H, Jaehde Ulrich
Dosing algorithm to target a predefined AUC in patients with primary central nervous system lymphoma receiving high dose methotrexate
Jörger M, Ferreri A, Krähenbühl S, Schellens J, Cerny T, Zucca E, Huitema A. Dosing algorithm to target a predefined AUC in patients with primary central nervous system lymphoma receiving high dose methotrexate. Br J Clin Pharmacol 2012; 73:240-7.
01.02.2012Dosing algorithm to target a predefined AUC in patients with primary central nervous system lymphoma receiving high dose methotrexate
01.02.2012Br J Clin Pharmacol 2012; 73:240-7
Jörger Markus, Ferreri Andrés J M, Krähenbühl Stephan, Schellens Jan H M, Cerny Thomas, Zucca Emanuele, Huitema Alwin D R
Germline polymorphisms in patients with advanced nonsmall cell lung cancer receiving first-line platinum-gemcitabine chemotherapy: a prospective clinical study
Jörger M, Beijnen J, Huitema A, Vincent A, Smits P, Doodeman V, Bard M, Haitjema T, Smit E, Baas P, Burgers S, Schellens J. Germline polymorphisms in patients with advanced nonsmall cell lung cancer receiving first-line platinum-gemcitabine chemotherapy: a prospective clinical study. Cancer 2011; 118:2466-75.
28.09.2011Germline polymorphisms in patients with advanced nonsmall cell lung cancer receiving first-line platinum-gemcitabine chemotherapy: a prospective clinical study
28.09.2011Cancer 2011; 118:2466-75
Jörger Markus, Beijnen Jos H, Huitema Alwin D R, Vincent Andrew, Smits Paul H M, Doodeman Valerie D, Bard Martin P L, Haitjema Tjeerd J, Smit Egbert F, Baas Paul, Burgers Sjaak A, Schellens Jan H M
Population pharmacokinetics and pharmacodynamics of paclitaxel and carboplatin in ovarian cancer patients: a study by the European organization for research and treatment of cancer-pharmacology and molecular mechanisms group and new drug development group
Jörger M, Hollema H, Féty R, Van der Vijgh W, Hempel G, Chatelut E, Karlsson M, Wilkins J, Tranchand B, Schrijvers A, Twelves C, Beijnen J, Boddy A, Calvert H, Jodrell D, Huitema A, Richel D, Dittrich C, Pavlidis N, Briasoulis E, Vermorken J, Strocchi E, Martoni A, Sorio R, Sleeboom H, Izquierdo M, Schellens J. Population pharmacokinetics and pharmacodynamics of paclitaxel and carboplatin in ovarian cancer patients: a study by the European organization for research and treatment of cancer-pharmacology and molecular mechanisms group and new drug development group. Clinical cancer research : an official journal of the American Association for Cancer Research 2007; 13:6410-8.
01.11.2007Population pharmacokinetics and pharmacodynamics of paclitaxel and carboplatin in ovarian cancer patients: a study by the European organization for research and treatment of cancer-pharmacology and molecular mechanisms group and new drug development group
01.11.2007Clinical cancer research : an official journal of the American Association for Cancer Research 2007; 13:6410-8
Jörger Markus, Hollema Harry, Féty Régine, Van der Vijgh Wjf J F, Hempel Georg, Chatelut Etienne, Karlsson Mats, Wilkins Justin, Tranchand Brigitte, Schrijvers Ad H G J, Twelves Christian, Beijnen Jos H, Boddy Alan V, Calvert Hilary, Jodrell Duncan I, Huitema Alwin D R, Richel Dick J, Dittrich Christian, Pavlidis Nikolas, Briasoulis Evangelos, Vermorken Jan B, Strocchi Elena, Martoni Andrea, Sorio Roberto, Sleeboom Henk P, Izquierdo Miguel A, Schellens Jan H M
Population pharmacokinetics and pharmacodynamics of doxorubicin and cyclophosphamide in breast cancer patients: a study by the EORTC-PAMM-NDDG
Jörger M, Féty R, de Bruijn E, Hempel G, Karlsson M, Tranchand B, Schrijvers A, Twelves C, Beijnen J, Schellens J, Jodrell D, Izquierdo M, Sleeboom H, Huitema A, Richel D, Dittrich C, Pavlidis N, Briasoulis E, Vermorken J, Strocchi E, Martoni A, Sorio R, EORTC-PAMM-NDDG. Population pharmacokinetics and pharmacodynamics of doxorubicin and cyclophosphamide in breast cancer patients: a study by the EORTC-PAMM-NDDG. Clinical pharmacokinetics 2007; 46:1051-68.
01.01.2007Population pharmacokinetics and pharmacodynamics of doxorubicin and cyclophosphamide in breast cancer patients: a study by the EORTC-PAMM-NDDG
01.01.2007Clinical pharmacokinetics 2007; 46:1051-68
Jörger Markus, Féty Régine, de Bruijn Ernst, Hempel Georg, Karlsson Mats, Tranchand Brigitte, Schrijvers Ad H G J, Twelves Chris, Beijnen Jos H, Schellens Jan H M, Jodrell Duncan I, Izquierdo Miguel A, Sleeboom Henk P, Huitema Alwin D R, Richel Dick J, Dittrich Christian, Pavlidis Nikolas, Briasoulis Evangelos, Vermorken Jan B, Strocchi Elena, Martoni Andrea, Sorio Roberto, EORTC-PAMM-NDDG
Quantitative effect of gender, age, liver function, and body size on the population pharmacokinetics of Paclitaxel in patients with solid tumors
Jörger M, Huitema A, van den Bongard D, Schellens J, Beijnen J. Quantitative effect of gender, age, liver function, and body size on the population pharmacokinetics of Paclitaxel in patients with solid tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 2006; 12:2150-7.
01.04.2006Quantitative effect of gender, age, liver function, and body size on the population pharmacokinetics of Paclitaxel in patients with solid tumors
01.04.2006Clinical cancer research : an official journal of the American Association for Cancer Research 2006; 12:2150-7
Jörger Markus, Huitema Alwin D R, van den Bongard Desiree H J G, Schellens Jan H M, Beijnen Jos H