Daniel D Pinschewer
Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T-cell responses to acute and chronic viral infection
Aparicio-Domingo P, Turley S, Pinschewer D, Cupedo T, Ludewig B, Papazian N, Alouche N, Favre S, Kallert S, Nguyen S, Buechler M, Cannelle H, Luther S. Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T-cell responses to acute and chronic viral infection. Eur J Immunol 2020
22.07.2020Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T-cell responses to acute and chronic viral infection
22.07.2020Eur J Immunol 2020
Aparicio-Domingo Patricia, Turley Shannon J, Pinschewer Daniel D, Cupedo Tom, Ludewig Burkhard, Papazian Natalie, Alouche Nagham, Favre Stéphanie, Kallert Sandra M, Nguyen Sylvain, Buechler Matthew B, Cannelle Hélène, Luther Sanjiv A
Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever
Remy M, Merkler D, Kaufmann B, Hanisch U, Bestmann L, Rieger T, Doras C, Fallet B, Kreutzfeldt M, Xu L, Regen T, Flatz L, Sahin M, Pinschewer D. Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever. Cell Host Microbe 2017; 22:354-365.e5.
17.08.2017Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever
17.08.2017Cell Host Microbe 2017; 22:354-365.e5
Remy Melissa M, Merkler Doron, Kaufmann Beat A, Hanisch Uwe-Karsten, Bestmann Lukas, Rieger Toni, Doras Camille, Fallet Benedict, Kreutzfeldt Mario, Xu Lifen, Regen Tommy, Flatz Lukas, Sahin Mehmet, Pinschewer Daniel D
Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection
Sommerstein R, Siegrist C, Lambert P, Bowden T, Coutard B, Rabah N, Meda P, Rigo D, Ter Meulen J, Igonet S, Bergthaler A, Sahin M, Fischer N, Magistrelli G, Malinge P, Remy M, Flatz L, Pinschewer D. Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection. PLoS Pathog 2015; 11:e1005276.
20.11.2015Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection
20.11.2015PLoS Pathog 2015; 11:e1005276
Sommerstein Rami, Siegrist Claire-Anne, Lambert Paul-Henri, Bowden Thomas A, Coutard Bruno, Rabah Nadia, Meda Paolo, Rigo Dorothée, Ter Meulen Jan, Igonet Sebastien, Bergthaler Andreas, Sahin Mehmet, Fischer Nicolas, Magistrelli Giovanni, Malinge Pauline, Remy Melissa M, Flatz Lukas, Pinschewer Daniel D
Protective efficacy of individual CD8+ T cell specificities in chronic viral infection
Johnson S, Bergthaler A, Graw F, Flatz L, Bonilla W, Siegrist C, Lambert P, Regoes R, Pinschewer D. Protective efficacy of individual CD8+ T cell specificities in chronic viral infection. J Immunol 2015; 194:1755-62.
07.01.2015Protective efficacy of individual CD8+ T cell specificities in chronic viral infection
07.01.2015J Immunol 2015; 194:1755-62
Johnson Susan, Bergthaler Andreas, Graw Frederik, Flatz Lukas, Bonilla Weldy V, Siegrist Claire-Anne, Lambert Paul-Henri, Regoes Roland R, Pinschewer Daniel D
Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses
Fasnacht N, Luther S, Ludewig B, Tacchini-Cottier F, MacDonald H, Pinschewer D, Kallert S, Onder L, Chai Q, Auderset F, Favre S, Koch U, Huang H, Radtke F. Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses. J Exp Med 2014; 211:2265-79.
13.10.2014Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses
13.10.2014J Exp Med 2014; 211:2265-79
Fasnacht Nicolas, Luther Sanjiv A, Ludewig Burkhard, Tacchini-Cottier Fabienne, MacDonald H Robson, Pinschewer Daniel D, Kallert Sandra, Onder Lucas, Chai Qian, Auderset Floriane, Favre Stéphanie, Koch Ute, Huang Hsin-Ying, Radtke Freddy
Gene-based vaccination with a mismatched envelope protects against simian immunodeficiency virus infection in nonhuman primates
Flatz L, Donaldson M, Schmidt S, Gall J, Pinschewer D, Letvin N, Rao S, Mascola J, Roederer M, Shen L, Asmal M, Todd J, Cheng C, Wang L, Foulds K, Ko S, Kong W, Roychoudhuri R, Shi W, Bao S, Nabel G. Gene-based vaccination with a mismatched envelope protects against simian immunodeficiency virus infection in nonhuman primates. J Virol 2012; 86:7760-70.
16.05.2012Gene-based vaccination with a mismatched envelope protects against simian immunodeficiency virus infection in nonhuman primates
16.05.2012J Virol 2012; 86:7760-70
Flatz Lukas, Donaldson Mitzi, Schmidt Stephen D, Gall Jason G D, Pinschewer Daniel D, Letvin Norman L, Rao Srinivas, Mascola John R, Roederer Mario, Shen Ling, Asmal Mohammed, Todd John-Paul, Cheng Cheng, Wang Lingshu, Foulds Kathryn E, Ko Sung-Youl, Kong Wing-Pui, Roychoudhuri Rahul, Shi Wei, Bao Saran, Nabel Gary J
Cross-species analysis of the replication complex of Old World arenaviruses reveals two nucleoprotein sites involved in L protein function
Kerber R, Rieger T, Busch C, Flatz L, Pinschewer D, Kümmerer B, Günther S. Cross-species analysis of the replication complex of Old World arenaviruses reveals two nucleoprotein sites involved in L protein function. J Virol 2011; 85:12518-28.
14.09.2011Cross-species analysis of the replication complex of Old World arenaviruses reveals two nucleoprotein sites involved in L protein function
14.09.2011J Virol 2011; 85:12518-28
Kerber Romy, Rieger Toni, Busch Carola, Flatz Lukas, Pinschewer Daniel D, Kümmerer Beate M, Günther Stephan
Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression
Bergthaler A, Flatz L, Hegazy A, Johnson S, Horvath E, Löhning M, Pinschewer D. Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression. Proc Natl Acad Sci USA 2010; 107:21641-6.
22.11.2010Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression
22.11.2010Proc Natl Acad Sci USA 2010; 107:21641-6
Bergthaler Andreas, Flatz Lukas, Hegazy Ahmed N, Johnson Susan, Horvath Edit, Löhning Max, Pinschewer Daniel D
Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes
Pinschewer D, Flatz L, Steinborn R, Horvath E, Fernandez M, Lutz H, Suter M, Bergthaler A. Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes. Int Immunol 2010; 22:749-56.
28.06.2010Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes
28.06.2010Int Immunol 2010; 22:749-56
Pinschewer Daniel D, Flatz Lukas, Steinborn Ralf, Horvath Edit, Fernandez Marylise, Lutz Hans, Suter Mark, Bergthaler Andreas
T cell-dependence of Lassa fever pathogenesis
Flatz L, Günther S, Hanisch U, Brück W, Kreutzfeldt M, Verschoor A, Bestmann L, Schedensack M, Regen T, Bergthaler A, Merkler D, Rieger T, Pinschewer D. T cell-dependence of Lassa fever pathogenesis. PLoS Pathog 2010; 6:e1000836.
26.03.2010T cell-dependence of Lassa fever pathogenesis
26.03.2010PLoS Pathog 2010; 6:e1000836
Flatz Lukas, Günther Stephan, Hanisch Uwe-Karsten, Brück Wolfgang, Kreutzfeldt Mario, Verschoor Admar, Bestmann Lukas, Schedensack Mariann, Regen Tommy, Bergthaler Andreas, Merkler Doron, Rieger Toni, Pinschewer Daniel D
Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity
Flatz L, Radbruch A, Levy F, Lambert P, Siegrist C, Restifo N, Löhning M, Ochsenbein A, Nabel G, Broek M, Kochanek S, Hegazy A, Bergthaler A, Verschoor A, Claus C, Fernandez M, Gattinoni L, Johnson S, Kreppel F, Pinschewer D. Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity. Nat Med 2010; 16:339-45.
07.02.2010Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity
07.02.2010Nat Med 2010; 16:339-45
Flatz Lukas, Radbruch Andreas, Levy Frederic, Lambert Paul-Henri, Siegrist Claire-Anne, Restifo Nicholas P, Löhning Max, Ochsenbein Adrian F, Nabel Gary J, Broek Maries van den, Kochanek Stefan, Hegazy Ahmed N, Bergthaler Andreas, Verschoor Admar, Claus Christina, Fernandez Marylise, Gattinoni Luca, Johnson Susan, Kreppel Florian, Pinschewer Daniel D
Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions
Hegazy A, Radbruch A, Pinschewer D, Flatz L, Bergthaler A, Fröhlich A, Panse I, Helmstetter C, Peine M, Löhning M. Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions. Immunity 2010; 32:116-28.
14.01.2010Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions
14.01.2010Immunity 2010; 32:116-28
Hegazy Ahmed N, Radbruch Andreas, Pinschewer Daniel D, Flatz Lukas, Bergthaler Andreas, Fröhlich Anja, Panse Isabel, Helmstetter Caroline, Peine Michael, Löhning Max
Impaired antibody response causes persistence of prototypic T cell-contained virus
Bergthaler A, Siegrist C, Odermatt B, Verbeek J, Senn B, Fitsche A, Fernandez M, Horvath E, Sommerstein R, Merkler D, Eschli B, Fink K, Holdener M, Hegazy A, Verschoor A, Flatz L, Pinschewer D. Impaired antibody response causes persistence of prototypic T cell-contained virus. PLoS Biol 2009; 7:e1000080.
07.04.2009Impaired antibody response causes persistence of prototypic T cell-contained virus
07.04.2009PLoS Biol 2009; 7:e1000080
Bergthaler Andreas, Siegrist Claire-Anne, Odermatt Bernhard, Verbeek J Sjef, Senn Beatrice M, Fitsche André, Fernandez Marylise, Horvath Edit, Sommerstein Rami, Merkler Doron, Eschli Bruno, Fink Katja, Holdener Martin, Hegazy Ahmed N, Verschoor Admar, Flatz Lukas, Pinschewer Daniel D
Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA
Flatz L, Bergthaler A, de la Torre J, Pinschewer D. Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA. Proc Natl Acad Sci USA 2006; 103:4663-8.
13.03.2006Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA
13.03.2006Proc Natl Acad Sci USA 2006; 103:4663-8
Flatz Lukas, Bergthaler Andreas, de la Torre Juan Carlos, Pinschewer Daniel D