Qian Chai
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands
Chung J, Onder L, Yan M, Reddy P, Blazar B, Huang A, Brennan T, Bishop D, Ludewig B, Siebel C, Radtke F, Luther S, Chai Q, Tran I, Ebens C, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Maillard I. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. J Clin Invest 2017; 127:1574-1588.
20.03.2017Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands
20.03.2017J Clin Invest 2017; 127:1574-1588
Chung Jooho, Onder Lucas, Yan Minhong, Reddy Pavan, Blazar Bruce R, Huang Alex Y, Brennan Todd V, Bishop D Keith, Ludewig Burkhard, Siebel Christian W, Radtke Freddy, Luther Sanjiv A, Chai Qian, Tran Ivy T, Ebens Christen L, Perkey Eric, Radojcic Vedran, Koch Ute, Scarpellino Leonardo, Tong Alexander, Allen Frederick, Wood Sherri, Feng Jiane, Friedman Ann, Granadier David, Maillard Ivan
Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs
Gil Cruz C, Scandella E, Ikuta K, Cui G, Abe S, McCoy K, Geuking M, Lang P, Novkovic M, Cheng H, Cupovic J, Chai Q, Onder L, Pérez Shibayama C, Ludewig B. Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs. Nat Immunol 2016; 17:1388-1396.
31.10.2016Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs
31.10.2016Nat Immunol 2016; 17:1388-1396
Gil Cruz Cristina, Scandella Elke, Ikuta Koichi, Cui Guangwei, Abe Shinya, McCoy Kathy D, Geuking Markus B, Lang Philipp A, Novkovic Mario, Cheng Hung-Wei, Cupovic Jovana, Chai Qian, Onder Lucas, Pérez Shibayama Christian Ivan, Ludewig Burkhard
Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction
Onder L, Waisman A, Becher B, Ledermann B, Mair F, Maier R, Bomze D, Novkovic M, Caviezel-Firner S, Cheng H, Chai Q, Scandella E, Nindl V, Ludewig B. Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction. Eur J Immunol 2015
14.05.2015Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction
14.05.2015Eur J Immunol 2015
Onder Lucas, Waisman Ari, Becher Burkhard, Ledermann Birgit, Mair Florian, Maier Reinhard, Bomze David, Novkovic Mario, Caviezel-Firner Sonja, Cheng Hung-Wei, Chai Qian, Scandella Elke, Nindl Veronika, Ludewig Burkhard
Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses
Fasnacht N, Luther S, Ludewig B, Tacchini-Cottier F, MacDonald H, Pinschewer D, Kallert S, Onder L, Chai Q, Auderset F, Favre S, Koch U, Huang H, Radtke F. Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses. J Exp Med 2014; 211:2265-79.
13.10.2014Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses
13.10.2014J Exp Med 2014; 211:2265-79
Fasnacht Nicolas, Luther Sanjiv A, Ludewig Burkhard, Tacchini-Cottier Fabienne, MacDonald H Robson, Pinschewer Daniel D, Kallert Sandra, Onder Lucas, Chai Qian, Auderset Floriane, Favre Stéphanie, Koch Ute, Huang Hsin-Ying, Radtke Freddy
IFN-γ-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi
Pérez Shibayama C, López-Macías C, Isibasi A, Waisman A, Regen T, Scandella E, Onder L, Chai Q, Hisaki E, Cervantes-Barragan L, Pastelin-Palacios R, Gil Cruz C, Ludewig B. IFN-γ-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi. J Immunol 2014; 192:5192-200.
28.04.2014IFN-γ-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi
28.04.2014J Immunol 2014; 192:5192-200
Pérez Shibayama Christian Ivan, López-Macías Constantino, Isibasi Armando, Waisman Ari, Regen Tommy, Scandella Elke, Onder Lucas, Chai Qian, Hisaki Emiliano, Cervantes-Barragan Luisa, Pastelin-Palacios Rodolfo, Gil Cruz Cristina, Ludewig Burkhard
Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity
Chai Q, Hehlgans T, Stein J, Rülicke T, Thiel V, Luther S, Sparwasser T, Danuser R, Cupovic J, Pérez Shibayama C, Gil Cruz C, Scandella E, Onder L, Ludewig B. Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity 2013; 38:1013-24.
25.04.2013Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity
25.04.2013Immunity 2013; 38:1013-24
Chai Qian, Hehlgans Thomas, Stein Jens V, Rülicke Thomas, Thiel Volker, Luther Sanjiv A, Sparwasser Tim, Danuser Renzo, Cupovic Jovana, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Scandella Elke, Onder Lucas, Ludewig Burkhard
Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation.
Onder L, Danuser R, Scandella E, Firner S, Chai Q, Hehlgans T, Stein J, Ludewig B. Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation. J Exp Med 2013; 210:465-73.
18.02.2013Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation.
18.02.2013J Exp Med 2013; 210:465-73
Onder Lucas, Danuser Renzo, Scandella Elke, Firner Sonja, Chai Qian, Hehlgans Thomas, Stein Jens V, Ludewig Burkhard
IL-7-producing stromal cells are critical for lymph node remodeling
Onder L, Coles M, Cupedo T, Westermann J, Kaye P, Richie E, Halin C, Hoorweg K, Iolyeva M, Chai Q, Scandella E, Narang P, Ludewig B. IL-7-producing stromal cells are critical for lymph node remodeling. Blood 2012; 120:4675-83.
06.09.2012IL-7-producing stromal cells are critical for lymph node remodeling
06.09.2012Blood 2012; 120:4675-83
Onder Lucas, Coles Mark, Cupedo Tom, Westermann Jürgen, Kaye Paul, Richie Ellen, Halin Cornelia, Hoorweg Kerim, Iolyeva Maria, Chai Qian, Scandella Elke, Narang Priyanka, Ludewig Burkhard
A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo.
Onder L, Scandella E, Chai Q, Firner S, Mayer C, Sparwasser T, Thiel V, Rülicke T, Ludewig B. A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo. Front Immunol 2011; 2:50.
12.10.2011A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo.
12.10.2011Front Immunol 2011; 2:50
Onder Lucas, Scandella Elke, Chai Qian, Firner Sonja, Mayer Christian T, Sparwasser Tim, Thiel Volker, Rülicke Thomas, Ludewig Burkhard