Hubert Kalbacher
Pulmonary Surfactant Proteins Are Inhibited by Immunoglobulin A Autoantibodies in Severe COVID-19.
Sinnberg T, Lichtensteiger C, Ali O, Pop O, Risch L, Brugger S, Velic A, Bomze D, Kohler P, Vernazza P, Albrich W, Kahlert C, Abdou M, Wyss N, Hofmeister K, Niessner H, Zinner C, Gilardi M, Tzankov A, Röcken M, Dulovic A, Shambat S, Ruetalo N, Buehler P, Scheier T, Jochum W, Kern L, Henz S, Schneider T, Kuster G, Lampart M, Siegemund M, Bingisser R, Schindler M, Schneiderhan-Marra N, Kalbacher H, McCoy K, Spengler W, Brutsche M, Macek B, Twerenbold R, Penninger J, Matter M, Flatz L, Jochum A. Pulmonary Surfactant Proteins Are Inhibited by Immunoglobulin A Autoantibodies in Severe COVID-19. Am J Respir Crit Care Med 2023; 207:38-49.
01.01.2023Pulmonary Surfactant Proteins Are Inhibited by Immunoglobulin A Autoantibodies in Severe COVID-19.
01.01.2023Am J Respir Crit Care Med 2023; 207:38-49
Sinnberg Tobias, Lichtensteiger Christa, Ali Omar Hasan, Pop Oltin T, Risch Lorenz, Brugger Silvio D, Velic Ana, Bomze David, Kohler Philipp, Vernazza Pietro, Albrich Werner, Kahlert Christian, Abdou Marie-Therese, Wyss Nina, Hofmeister Kathrin, Niessner Heike, Zinner Carl, Gilardi Mara, Tzankov Alexandar, Röcken Martin, Dulovic Alex, Shambat Srikanth Mairpady, Ruetalo Natalia, Buehler Philipp K, Scheier Thomas C, Jochum Wolfram, Kern Lukas, Henz Samuel, Schneider Tino, Kuster Gabriela M, Lampart Maurin, Siegemund Martin, Bingisser Roland, Schindler Michael, Schneiderhan-Marra Nicole, Kalbacher Hubert, McCoy Kathy D, Spengler Werner, Brutsche Martin H, Macek Boris, Twerenbold Raphael, Penninger Josef M, Matter Matthias S, Flatz Lukas, Jochum Ann-Kristin
Human cytomegalovirus infection interferes with major histocompatibility complex type II maturation and endocytic proteases in dendritic cells at multiple levels
Kessler T, Reich M, Jahn G, Tolosa E, Beck A, Kalbacher H, Overkleeft H, Schempp S, Driessen C. Human cytomegalovirus infection interferes with major histocompatibility complex type II maturation and endocytic proteases in dendritic cells at multiple levels. The Journal of general virology 2008; 89:2427-36.
01.10.2008Human cytomegalovirus infection interferes with major histocompatibility complex type II maturation and endocytic proteases in dendritic cells at multiple levels
01.10.2008The Journal of general virology 2008; 89:2427-36
Kessler Tobias, Reich Michael, Jahn Gerhard, Tolosa Eva, Beck Alexander, Kalbacher Hubert, Overkleeft Herman, Schempp Susanne, Driessen Christoph
A novel cell penetrating aspartic protease inhibitor blocks processing and presentation of tetanus toxoid more efficiently than pepstatin A
Zaidi N, Burster T, Sommandas V, Herrmann T, Boehm B, Driessen C, Voelter W, Kalbacher H. A novel cell penetrating aspartic protease inhibitor blocks processing and presentation of tetanus toxoid more efficiently than pepstatin A. Biochemical and biophysical research communications 2007; 364:243-9.
14.12.2007A novel cell penetrating aspartic protease inhibitor blocks processing and presentation of tetanus toxoid more efficiently than pepstatin A
14.12.2007Biochemical and biophysical research communications 2007; 364:243-9
Zaidi Nousheen, Burster Timo, Sommandas Vinod, Herrmann Timo, Boehm Bernhard O, Driessen Christoph, Voelter Wolfgang, Kalbacher Hubert
Design of protease-resistant myelin basic protein-derived peptides by cleavage site directed amino acid substitutions
Burster T, Kalbacher H, Verhelst S, Weber E, Falk K, Rotzschke O, Dunn S, Boehm B, Marin-Esteban V, Driessen C. Design of protease-resistant myelin basic protein-derived peptides by cleavage site directed amino acid substitutions. Biochemical pharmacology 2007; 74:1514-23.
15.11.2007Design of protease-resistant myelin basic protein-derived peptides by cleavage site directed amino acid substitutions
15.11.2007Biochemical pharmacology 2007; 74:1514-23
Burster Timo, Kalbacher Hubert, Verhelst Steven H L, Weber Ekkehard, Falk Kirsten, Rotzschke Olaf, Dunn Shannon, Boehm Bernhard O, Marin-Esteban Viviana, Driessen Christoph
A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles
Zaidi N, Herrmann T, Baechle D, Schleicher S, Gogel J, Driessen C, Voelter W, Kalbacher H. A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles. The FEBS journal 2007; 274:3138-49.
01.06.2007A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles
01.06.2007The FEBS journal 2007; 274:3138-49
Zaidi Nousheen, Herrmann Timo, Baechle Daniel, Schleicher Sabine, Gogel Jeannette, Driessen Christoph, Voelter Wolfgang, Kalbacher Hubert
Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro
Burster T, Tolosa E, Overkleeft H, Kalbacher H, Youssef S, Boehm B, Falk K, Roetzschke O, Reich M, Baechle D, Øren A, Poeschel S, Beck A, Driessen C. Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro. Immunology 2007; 121:82-93.
01.05.2007Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro
01.05.2007Immunology 2007; 121:82-93
Burster Timo, Tolosa Eva, Overkleeft Herman, Kalbacher Hubert, Youssef Sawsan, Boehm Bernhard O, Falk Kirsten, Roetzschke Olaf, Reich Michael, Baechle Daniel, Øren Anita, Poeschel Simone, Beck Alexander, Driessen Christoph
Endocytosis targets exogenous material selectively to cathepsin S in live human dendritic cells, while cell-penetrating peptides mediate nonselective transport to cysteine cathepsins
Reich M, van Swieten P, Sommandas V, Kraus M, Fischer R, Weber E, Kalbacher H, Overkleeft H, Driessen C. Endocytosis targets exogenous material selectively to cathepsin S in live human dendritic cells, while cell-penetrating peptides mediate nonselective transport to cysteine cathepsins. Journal of leukocyte biology 2007; 81:990-1001.
01.04.2007Endocytosis targets exogenous material selectively to cathepsin S in live human dendritic cells, while cell-penetrating peptides mediate nonselective transport to cysteine cathepsins
01.04.2007Journal of leukocyte biology 2007; 81:990-1001
Reich Michael, van Swieten Paul F, Sommandas Vinod, Kraus Marianne, Fischer Rainer, Weber Ekkehard, Kalbacher Hubert, Overkleeft Herman S, Driessen Christoph
Specificity of human cathepsin S determined by processing of peptide substrates and MHC class II-associated invariant chain
Rückrich T, Driessen C, Reich M, Melms A, Beck A, Wiederanders B, Schilling K, Stevanovic S, Müller M, Cansier A, Brandenburg J, Kalbacher H. Specificity of human cathepsin S determined by processing of peptide substrates and MHC class II-associated invariant chain. Biol Chem 2006; 387:1503-11.
01.10.2006Specificity of human cathepsin S determined by processing of peptide substrates and MHC class II-associated invariant chain
01.10.2006Biol Chem 2006; 387:1503-11
Rückrich Thomas, Driessen Christoph, Reich Michael, Melms Arthur, Beck Alexander, Wiederanders Bernd, Schilling Klaus, Stevanovic Stefan, Müller Margret, Cansier Alexander, Brandenburg Jens, Kalbacher Hubert
Differential processing of autoantigens in lysosomes from human monocyte-derived and peripheral blood dendritic cells
Burster T, Overkleeft H, Weber E, Häring H, Kalbacher H, Kraus M, Reich M, Weissert R, Schnorrer P, Tolosa E, Beck A, Driessen C. Differential processing of autoantigens in lysosomes from human monocyte-derived and peripheral blood dendritic cells. Journal of immunology (Baltimore, Md. : 1950) 2005; 175:5940-9.
01.11.2005Differential processing of autoantigens in lysosomes from human monocyte-derived and peripheral blood dendritic cells
01.11.2005Journal of immunology (Baltimore, Md. : 1950) 2005; 175:5940-9
Burster Timo, Overkleeft Herman, Weber Ekkehard, Häring Hans-Ulrich, Kalbacher Hubert, Kraus Marianne, Reich Michael, Weissert Robert, Schnorrer Petra, Tolosa Eva, Beck Alexander, Driessen Christoph
Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
Dengjel J, Rammensee H, Driessen C, Brock R, Kalbacher H, Brandenburg J, Altenberend F, Kreymborg K, Müller M, Kraus M, Reich M, Fischer R, Schoor O, Stevanovic S. Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proceedings of the National Academy of Sciences of the United States of America 2005; 102:7922-7.
31.05.2005Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
31.05.2005Proceedings of the National Academy of Sciences of the United States of America 2005; 102:7922-7
Dengjel Jörn, Rammensee Hans-Georg, Driessen Christoph, Brock Roland, Kalbacher Hubert, Brandenburg Jens, Altenberend Florian, Kreymborg Katharina, Müller Margret, Kraus Marianne, Reich Michael, Fischer Rainer, Schoor Oliver, Stevanovic Stefan
Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases
van Swieten P, Ploegh H, van der Marel G, Driessen C, Leeuwenburgh M, Kalbacher H, Wong C, Reich M, Kessler B, van den Nieuwendijk A, Maehr R, Overkleeft H. Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases. Bioorganic & medicinal chemistry letters 2004; 14:3131-4.
21.06.2004Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases
21.06.2004Bioorganic & medicinal chemistry letters 2004; 14:3131-4
van Swieten Paul F, Ploegh Hidde L, van der Marel Gijsbert A, Driessen Christoph, Leeuwenburgh Michiel A, Kalbacher Hubert, Wong Chung-Sing, Reich Michael, Kessler Benedikt M, van den Nieuwendijk Adrianus M C H, Maehr Rene, Overkleeft Herman S
Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes
Burster T, Kalbacher H, Stevanovic S, Lehmann R, Melms A, Wiendl H, Schwarz G, Brandenburg J, Reich M, Lautwein A, Falk K, Rotzschke O, Marin-Esteban V, Tolosa E, Beck A, Driessen C. Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes. Journal of immunology (Baltimore, Md. : 1950) 2004; 172:5495-503.
01.05.2004Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes
01.05.2004Journal of immunology (Baltimore, Md. : 1950) 2004; 172:5495-503
Burster Timo, Kalbacher Hubert, Stevanovic Stefan, Lehmann Rainer, Melms Arthur, Wiendl Heinz, Schwarz Gerold, Brandenburg Jens, Reich Michael, Lautwein Alfred, Falk Kirsten, Rotzschke Olaf, Marin-Esteban Viviana, Tolosa Eva, Beck Alexander, Driessen Christoph
Human B lymphoblastoid cells contain distinct patterns of cathepsin activity in endocytic compartments and regulate MHC class II transport in a cathepsin S-independent manner
Lautwein A, Nordheim A, Kalbacher H, Weber E, Kammer W, Schwarz G, Overkleeft H, Brandenburg J, Burster T, Reich M, Kraus M, Driessen C. Human B lymphoblastoid cells contain distinct patterns of cathepsin activity in endocytic compartments and regulate MHC class II transport in a cathepsin S-independent manner. Journal of leukocyte biology 2004; 75:844-55.
01.05.2004Human B lymphoblastoid cells contain distinct patterns of cathepsin activity in endocytic compartments and regulate MHC class II transport in a cathepsin S-independent manner
01.05.2004Journal of leukocyte biology 2004; 75:844-55
Lautwein Alfred, Nordheim Alfred, Kalbacher Hubert, Weber Ekkehard, Kammer Winfried, Schwarz Gerold, Overkleeft Herman S, Brandenburg J, Burster Timo, Reich Michael, Kraus Marianne, Driessen Christoph
Inflammatory stimuli recruit cathepsin activity to late endosomal compartments in human dendritic cells
Lautwein A, Burster T, Lennon-Duménil A, Overkleeft H, Weber E, Kalbacher H, Driessen C. Inflammatory stimuli recruit cathepsin activity to late endosomal compartments in human dendritic cells. European journal of immunology 2002; 32:3348-57.
01.12.2002Inflammatory stimuli recruit cathepsin activity to late endosomal compartments in human dendritic cells
01.12.2002European journal of immunology 2002; 32:3348-57
Lautwein Alfred, Burster Timo, Lennon-Duménil Ana-Maria, Overkleeft Herman S, Weber Ekkehard, Kalbacher Hubert, Driessen Christoph
Characterization of legumain
Schwarz G, Brandenburg J, Reich M, Burster T, Driessen C, Kalbacher H. Characterization of legumain. Biological chemistry 2002; 383:1813-6.
01.11.2002Characterization of legumain
01.11.2002Biological chemistry 2002; 383:1813-6
Schwarz Gerold, Brandenburg Jens, Reich Michael, Burster Timo, Driessen Christoph, Kalbacher Hubert
Modulation of the endosomal and lysosomal distribution of cathepsins B, L and S in human monocytes/macrophages
Schmid H, Sauerbrei R, Schwarz G, Weber E, Kalbacher H, Driessen C. Modulation of the endosomal and lysosomal distribution of cathepsins B, L and S in human monocytes/macrophages. Biological chemistry 2002; 383:1277-83.
01.07.2002Modulation of the endosomal and lysosomal distribution of cathepsins B, L and S in human monocytes/macrophages
01.07.2002Biological chemistry 2002; 383:1277-83
Schmid Heide, Sauerbrei Ramona, Schwarz Gerold, Weber Ekkehard, Kalbacher Hubert, Driessen Christoph
Specific role for cathepsin S in the generation of antigenic peptides in vivo
Plüger E, Boes M, Alfonso C, Schröter C, Kalbacher H, Ploegh H, Driessen C. Specific role for cathepsin S in the generation of antigenic peptides in vivo. European journal of immunology 2002; 32:467-76.
01.02.2002Specific role for cathepsin S in the generation of antigenic peptides in vivo
01.02.2002European journal of immunology 2002; 32:467-76
Plüger Esther B E, Boes Marianne, Alfonso Christopher, Schröter Christian J, Kalbacher Hubert, Ploegh Hidde L, Driessen Christoph