Publication
Laryngopharyngeal reflux in chronic obstructive pulmonary disease - a multi-centre study
Journal Paper/Review - Aug 21, 2020
Sanchez Julia, Schumann Desiree M, Karakioulaki Meropi, Papakonstantinou Eleni, Rassouli Frank, Frasnelli Matthias, Brutsche Martin, Tamm Michael, Stolz Daiana
Units
PubMed
Doi
Citation
Type
Journal
Publication Date
Issn Electronic
Pages
Brief description/objective
Reflux of gastric content has been associated with recurrent exacerbations of chronic obstructive pulmonary disease (COPD). We aimed to assess the prevalence of laryngopharyngeal reflux (LPR) in COPD and if LPR is a contributing factor to clinically relevant outcomes in COPD. We evaluated a total of 193 COPD patients (GOLD I-IV) with a 24-h laryngo-pharyngeal pΗ-monitor. LPR was observed in 65.8% of COPD patients and it was not significantly associated with clinically relevant outcomes of COPD. Treatment with PPI significantly decreased the upright RYAN score (p = 0.047) without improving lung function. Furthermore, the presence or severity of LPR cannot be diagnosed based solely on symptoms and questionnaires.