Publication

T-cell-rich B-cell non-Hodgkin's lymphoma mimicking Hodgkin's disease

Journal Paper/Review - Apr 1, 1999

Units
PubMed

Citation
Bättig B, Mueller-Garamvoelgyi E, Cogliatti S, Schmid U, Kappeler A, Cerny T, Laissue J, Fey M. T-cell-rich B-cell non-Hodgkin's lymphoma mimicking Hodgkin's disease. Leukemia & lymphoma 1999; 33:393-8.
Type
Journal Paper/Review (English)
Journal
Leukemia & lymphoma 1999; 33
Publication Date
Apr 1, 1999
Issn Print
1042-8194
Pages
393-8
Brief description/objective

We report on a patient with recurrent T-cell-rich B-cell lymphoma (TCRBCL), initially misdiagnosed as a lymphocyte-rich Hodgkin's disease. This case exemplifies the diagnostic problems of TCRBCL and the need for immunophenotypic analysis to differentiate TCRBCL from Hodgkin's disease, nodular paragranuloma and peripheral T-cell lymphoma. A rather unusual aspect is the long disease-free interval between the excision of the node in and the late relapse in 1996. The significance of the abundant T-cell infiltration in this B-cell neoplasm will be discussed and the concepts concerning antitumor response will be reviewed. Based on epidemiological data and the clinical behaviour TCRBCL does not seem to represent a distinctive pathological entity.