T-cell-rich B-cell non-Hodgkin's lymphoma mimicking Hodgkin's disease

Publication

T-cell-rich B-cell non-Hodgkin's lymphoma mimicking Hodgkin's disease

Journal Paper/Review - Apr 1, 1999

Bättig B, Mueller-Garamvoelgyi E, Cogliatti S B, Schmid U, Kappeler A, Cerny Thomas, Laissue J A, Fey M F

Units

Medizinische Onkologie und Hämatologie

PubMed

10221522

Citation

Bättig B, Mueller-Garamvoelgyi E, Cogliatti S, Schmid U, Kappeler A, Cerny T, Laissue J, Fey M. T-cell-rich B-cell non-Hodgkin's lymphoma mimicking Hodgkin's disease. Leukemia & lymphoma 1999; 33:393-8.

Type

Journal Paper/Review (English)

Journal

Leukemia & lymphoma 1999; 33

Publication Date

Apr 1, 1999

Issn Print

1042-8194

Pages

393-8

Brief description/objective

We report on a patient with recurrent T-cell-rich B-cell lymphoma (TCRBCL), initially misdiagnosed as a lymphocyte-rich Hodgkin's disease. This case exemplifies the diagnostic problems of TCRBCL and the need for immunophenotypic analysis to differentiate TCRBCL from Hodgkin's disease, nodular paragranuloma and peripheral T-cell lymphoma. A rather unusual aspect is the long disease-free interval between the excision of the node in and the late relapse in 1996. The significance of the abundant T-cell infiltration in this B-cell neoplasm will be discussed and the concepts concerning antitumor response will be reviewed. Based on epidemiological data and the clinical behaviour TCRBCL does not seem to represent a distinctive pathological entity.