Publication
Advanced diffusion imaging reveals microstructural characteristics of primary CNS lymphoma, allowing differentiation from glioblastoma.
Journal Paper/Review - Jun 8, 2024
Würtemberger Urs, Diebold Martin, Rau Alexander, Akgün Veysel, Becker Lucas, Beck Jürgen, Reinacher Peter C, Taschner Christian A, Reisert Marco, Fehrenbacher Luca, Erny Daniel, Scherer Florian, Hohenhaus Marc, Urbach Horst, Demerath Theo
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Brief description/objective
Primary CNS lymphoma (PCNSL) and glioblastoma (GBM) both represent frequent intracranial malignancies with differing clinical management. However, distinguishing PCNSL from GBM with conventional MRI can be challenging when atypical imaging features are present. We employed advanced dMRI for noninvasive characterization of the microstructure of PCNSL and differentiation from GBM as the most frequent primary brain malignancy.