Advanced diffusion imaging reveals microstructural characteristics of primary CNS lymphoma, allowing differentiation from glioblastoma.

Publication

Advanced diffusion imaging reveals microstructural characteristics of primary CNS lymphoma, allowing differentiation from glioblastoma.

Journal Paper/Review - Jun 8, 2024

Würtemberger Urs, Diebold Martin, Rau Alexander, Akgün Veysel, Becker Lucas, Beck Jürgen, Reinacher Peter C, Taschner Christian A, Reisert Marco, Fehrenbacher Luca, Erny Daniel, Scherer Florian, Hohenhaus Marc, Urbach Horst, Demerath Theo

Citation

Würtemberger U, Diebold M, Rau A, Akgün V, Becker L, Beck J, Reinacher P, Taschner C, Reisert M, Fehrenbacher L, Erny D, Scherer F, Hohenhaus M, Urbach H, Demerath T. Advanced diffusion imaging reveals microstructural characteristics of primary CNS lymphoma, allowing differentiation from glioblastoma. Neurooncol Adv 2024; 6:vdae093.

Type

Journal Paper/Review (English)

Journal

Neurooncol Adv 2024; 6

Publication Date

Jun 8, 2024

Issn Electronic

2632-2498

Pages

vdae093

Brief description/objective

Primary CNS lymphoma (PCNSL) and glioblastoma (GBM) both represent frequent intracranial malignancies with differing clinical management. However, distinguishing PCNSL from GBM with conventional MRI can be challenging when atypical imaging features are present. We employed advanced dMRI for noninvasive characterization of the microstructure of PCNSL and differentiation from GBM as the most frequent primary brain malignancy.