Publication
Enrichment of Nanofiber Hydrogel Composite with Fractionated Fat Promotes Regenerative Macrophage Polarization and Vascularization for Soft-Tissue Engineering.
Journal Paper/Review - Mar 1, 2022
Henn Dominic, Fischer Katharina S, Chen Kellen, Greco Autumn H, Martin Russell A, Sivaraj Dharshan, Trotsyuk Artem A, Mao Hai-Quan, Reddy Sashank K, Kneser Ulrich, Gurtner Geoffrey C, Schmidt Volker, Sacks Justin M
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Issn Electronic
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Brief description/objective
Fractionated fat has been shown to promote dermal regeneration; however, the use of fat grafting for reconstruction of soft-tissue defects is limited because of volume loss over time. The authors have developed a novel approach for engineering of vascularized soft tissue using an injectable nanofiber hydrogel composite enriched with fractionated fat.