Publication

Temporal trends in cardiovascular risk factors prevalence in patients with myocardial infarction

Journal Paper/Review - Nov 30, 2020

Units
PubMed
Doi

Citation
Cimci M, Witassek F, Radovanovic D, Rickli H, Pedrazzini G, Erne P, Muller O, Eberli F, Roffi M. Temporal trends in cardiovascular risk factors prevalence in patients with myocardial infarction. Eur J Clin Invest 2020:e13466.
Type
Journal Paper/Review (English)
Journal
Eur J Clin Invest 2020
Publication Date
Nov 30, 2020
Issn Electronic
1365-2362
Pages
e13466
Brief description/objective

INTRODUCTION AND OBJECTIVES
Little is known about changes in cardiovascular risk factors (CVRF) profile over time in patients presenting with acute myocardial infarction (AMI).

METHODS
We assessed changes in age and CVRF profile in consecutive AMI patients enrolled in the Swiss nationwide AMIS Plus registry between January 1, 1997 and December 31, 2018.

RESULTS
A total of 57,995 AMI patients were included in the analysis. Mean age at presentation was 71.5±11.3 years for women and 63.9±12.8 years for men and did not change over time. Overall, the mean (standard deviation) number of CVRF increased from 1.76 (1.07) in 1997/98 to 2.26 (1.10) in 2017/18 in men (P <0.001) while the corresponding rates in females were 1.83 (1.11) and 2.24 (1.08) (P <0.001). In terms of active smoking, no significant trend was detected for males while there was a significant increase in females (p<0.001). As a result, the gap in smoking rates between men and women presenting with AMI decreased from 19.9% (45.3% vs. 25.4%) in 1997/98 to 7.9% (41.2% vs. 33.3%) in 2017/18. Reassuring was the stability in terms of diabetes prevalence for both genders. Obesity was more prevalent over time in men while the prevalence of hypertension and dyslipidemia increased in both genders.

CONCLUSION
Among patients with AMI in Switzerland over two decades, age at presentation remained stable while the mean number of CVRF increased in both men and women. Striking was the increase in the prevalence of smoking in women, leading to a reduction of the gender gap over time.