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[Potential applications and significance of peripheral opioid analgesia]

Journal Paper/Review - Oct 1, 2005

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Citation
Oeltjenbruns J, Schäfer M. [Potential applications and significance of peripheral opioid analgesia]. Schmerz 2005; 19:447-52, 454-5.
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Type
Journal Paper/Review (Deutsch)
Journal
Schmerz 2005; 19
Publication Date
Oct 1, 2005
Issn Print
0932-433X
Issn Electronic
Pages
447-52, 454-5
Publisher
Brief description/objective

Recently, the local application of analgesic substances has attracted much interest and has become increasingly relevant in daily clinical practice. The lack of the well-known therapy-limiting central side effects of systemically administered opioids is a clear advantage of "peripheral opioid analgesia". Important prerequisites for the occurrence of peripheral analgesic effects of opioids are good accessibility of the painful site, presence of clinically relevant pain, signs of a local inflammation, exclusion of a fast systemic absorption, and adequately potent analgesic substances. This review gives an outline of recent experience with various clinical applications of "peripheral opioid analgesia".