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The role of postoperative thoracic radiotherapy and prophylactic cranial irradiation in early stage small cell lung cancer: Patient selection among ESTRO experts

Journal Paper/Review - Dec 27, 2019

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Citation
Putora P, Belderbos J, Dziadziuszko R, Le Pechoux C, McDonald F, Nestle U, Peeters S, Pöttgen C, Ramella S, Slotman B, Troost E, Van Houtte P, Widder J, Glatzer M, De Ruysscher D, Faivre-Finn C. The role of postoperative thoracic radiotherapy and prophylactic cranial irradiation in early stage small cell lung cancer: Patient selection among ESTRO experts. Radiother Oncol 2019; 145:45-48.
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Type
Journal Paper/Review (English)
Journal
Radiother Oncol 2019; 145
Publication Date
Dec 27, 2019
Issn Print
Issn Electronic
1879-0887
Pages
45-48
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Brief description/objective

BACKGROUND
The role of prophylactic cranial irradiation (PCI) and thoracic radiotherapy (TRT) is unclear in resected small cell lung cancer (SCLC).

METHODS
Thirteen European radiotherapy experts on SCLC were asked to describe their strategies on PCI and TRT for patients with resected SCLC. The treatment strategies were converted into decision trees and analyzed for consensus and discrepancies.

RESULTS
For patients with resected SCLC and positive lymph nodes most experts recommend prophylactic cranial irradiation and thoracic radiotherapy. For elderly patients with resected node negative SCLC, most experts do not recommend thoracic radiotherapy or prophylactic cranial irradiation.

CONCLUSION
PCI and TRT are considered in patients with resected SCLC and these treatments should be discussed with the patient in the context of shared decision-making.