Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

Publication

Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

Journal Paper/Review - Nov 18, 2019

Anthis Alexandre H C, Chavatte-Palmer Pascale, Jochum Wolfram, Wick Peter, Dommann Alex, Bürki-Turnherr Tina, Fischer Tina, Hornung René, Bertazzo Sergio, Lehner Sandro, Wildermuth Simon, Leschka Sebastian, Tsolaki Elena, Didierlaurent Louis, Staubli Samuel, Zboray Robert, Neels Antonia, Dietrich Dörthe, Manser Pius, Desbiolles Lotus May, Herrmann Inge K

Citation

Anthis A, Chavatte-Palmer P, Jochum W, Wick P, Dommann A, Bürki-Turnherr T, Fischer T, Hornung R, Bertazzo S, Lehner S, Wildermuth S, Leschka S, Tsolaki E, Didierlaurent L, Staubli S, Zboray R, Neels A, Dietrich D, Manser P, Desbiolles L, Herrmann I. Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure. Analyst 2019; 144:6850-6857.

Type

Journal Paper/Review (English)

Journal

Analyst 2019; 144

Publication Date

Nov 18, 2019

Issn Electronic

1364-5528

Pages

6850-6857

Brief description/objective

Despite its crucial role, the placenta is the least understood human organ. Recent clinical studies indicate a direct association between placental calcification and maternal and offspring health. This study reveals distinct characteristics of minerals formed during gestational ageing using cutting-edge nano-analytical characterization and paves the way for investigations focused on the identification of potential markers for disease risks in a clinical setting based on atypical placental mineral fingerprints.