Imaging Diagnosis and Follow-up of Advanced Prostate Cancer: Clinical Perspectives and State of the Art

Publication

Imaging Diagnosis and Follow-up of Advanced Prostate Cancer: Clinical Perspectives and State of the Art

Journal Paper/Review - Jun 25, 2019

Pérez-López Raquel, de Bono Johann, Morris Michael J, Omlin Aurelius, Vargas Hebert Alberto, Fanti Stefano, Oyen Wim J G, Padhani Anwar R, Tunariu Nina, Koh Dow-Mu

Citation

Pérez-López R, de Bono J, Morris M, Omlin A, Vargas H, Fanti S, Oyen W, Padhani A, Tunariu N, Koh D. Imaging Diagnosis and Follow-up of Advanced Prostate Cancer: Clinical Perspectives and State of the Art. Radiology 2019; 292:273-286.

Type

Journal Paper/Review (English)

Journal

Radiology 2019; 292

Publication Date

Jun 25, 2019

Issn Electronic

1527-1315

Pages

273-286

Brief description/objective

The management of advanced prostate cancer has changed substantially with the availability of multiple effective novel treatments, which has led to improved disease survival. In the era of personalized cancer treatments, more precise imaging may help physicians deliver better care. More accurate local staging and earlier detection of metastatic disease, accurate identification of oligometastatic disease, and optimal assessment of treatment response are areas where modern imaging is rapidly evolving and expanding. Next-generation imaging modalities, including whole-body MRI and molecular imaging with combined PET and CT and combined PET and MRI using novel radiopharmaceuticals, create new opportunities for imaging to support and refine management pathways in patients with advanced prostate cancer. This article demonstrates the potential and challenges of applying next-generation imaging to deliver the clinical promise of treatment breakthroughs.