Transient hypoxia and downregulation of circulating prohepcidin concentrations in healthy young men

Publication

Transient hypoxia and downregulation of circulating prohepcidin concentrations in healthy young men

Journal Paper/Review - Jan 1, 2007

Benedict Christian, Ghio Andrew J, Gehring Hartmut, Schultes Bernd, Peters Achim, Oltmanns Kerstin M

Units

Clinic for General, Visceral, Endocrine and Transplant Surgery

PubMed

17229646

Citation

Benedict C, Ghio A, Gehring H, Schultes B, Peters A, Oltmanns K. Transient hypoxia and downregulation of circulating prohepcidin concentrations in healthy young men. Haematologica 2007; 92:125-6.

Type

Journal Paper/Review (English)

Journal

Haematologica 2007; 92

Publication Date

Jan 1, 2007

Issn Electronic

1592-8721

Pages

125-6

Brief description/objective

To determine the impact of acute hypoxia on prohepcidin concentrations in humans, we measured concentrations of this peptide in serum collected during and after a transient period (30 min) of hypoxia and during normoxia. Prohepcidin concentrations were significantly lower 150 min after the end of hypoxia than after normoxia (p=0.028).