ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer

Publication

ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer

Journal Paper/Review - Mar 28, 2018

Nestle Ursula, LePéchoux Cécile, Putora Paul Martin, Manapov Farkhad, McDonald Fiona, Faivre-Finn Corinne, Ramella Sara, Slotman Ben, Hurkmans Coen, Lievens Yolande, Peeters Stephanie, Dziadiuszko Rafal, Pöttgen Christoph, Belderbos Jose, Geets Xavier, Ricardi Umberto, De Ruysscher Dirk, Van Houtte Paul

Citation

Nestle U, LePéchoux C, Putora P, Manapov F, McDonald F, Faivre-Finn C, Ramella S, Slotman B, Hurkmans C, Lievens Y, Peeters S, Dziadiuszko R, Pöttgen C, Belderbos J, Geets X, Ricardi U, De Ruysscher D, Van Houtte P. ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer. Radiother Oncol 2018; 127:1-5.

Type

Journal Paper/Review (English)

Journal

Radiother Oncol 2018; 127

Publication Date

Mar 28, 2018

Issn Electronic

1879-0887

Pages

1-5

Brief description/objective

Radiotherapy (RT) plays a major role in the curative treatment of locally advanced non-small cell lung cancer (NSCLC). Therefore, the ACROP committee was asked by the ESTRO to provide recommendations on target volume delineation for standard clinical scenarios in definitive (chemo)radiotherapy (RT) and adjuvant RT for locally advanced NSCLC. The guidelines given here are a result of the evaluation of a structured questionnaire followed by a consensus discussion, voting and writing procedure within the committee. Hence, we provide advice for methods and time-points of diagnostics and imaging before the start of treatment planning and for the mandatory and optional imaging to be used for planning itself. Concerning target volumes, recommendations are given for GTV delineation of primary tumour and lymph nodes followed by issues related to the delineation of CTVs for definitive and adjuvant radiotherapy. In the context of PTV delineation, recommendations about the management of geometric uncertainties and target motion are given. We further provide our opinions on normal tissue delineation and organisational and responsibility questions in the process of target volume delineation. This guideline intends to contribute to the standardisation and optimisation of the process of RT treatment planning for clinical practice and prospective studies.