Superficial and deep retinal foveal avascular zone OCTA findings of non-infectious anterior and posterior uveitis

Publication

Superficial and deep retinal foveal avascular zone OCTA findings of non-infectious anterior and posterior uveitis

Journal Paper/Review - Jul 6, 2018

Waizel Maria, Todorova Margarita, Terrada Celine, LeHoang Phuc, Massamba Natalie, Bodaghi Bahram

Citation

Waizel M, Todorova M, Terrada C, LeHoang P, Massamba N, Bodaghi B. Superficial and deep retinal foveal avascular zone OCTA findings of non-infectious anterior and posterior uveitis. Graefes Arch Clin Exp Ophthalmol 2018

Type

Journal Paper/Review (English)

Journal

Graefes Arch Clin Exp Ophthalmol 2018

Publication Date

Jul 6, 2018

Issn Electronic

1435-702X

Brief description/objective

PURPOSE
To compare the superficial (FAZ-S) and deep foveal avascular zones (FAZ-D) of non-infectious anterior and posterior uveitis to healthy controls, using optical coherence tomography angiography (OCTA).

METHODS
OCTA was performed on 74 eyes: 34 eyes with non-infectious posterior uveitis (with (post+CME) and without macular edema (post-CME)), 11 eyes with non-infectious anterior uveitis (with (ant+CME) and without macular edema (ant-CME)), and the control group which included 29 healthy eyes.

RESULTS
Eyes suffering from non-infectious posterior uveitis presented with significantly larger FAZ-D when compared to healthy controls, both in the presence or in the absence of macular edema (p < 0.001). In the presence of macular edema, eyes presenting with anterior uveitis (ant+CME) also showed significantly larger FAZ-S (p = 0.03) and FAZ-D (p < 0.001), when compared to healthy controls. In the absence of macular edema, eyes with anterior uveitis cannot be distinguished from controls (p > 0.6).

CONCLUSION
The deep retinal foveal avascular zone seems to be enlarged in eyes presenting with non-infectious posterior uveitis, both in the presence or absence of macular edema.