Publication

Pathogenesis and therapy of cutaneous lymphomas--progress or impasse?

Journal Paper/Review - May 1, 2006

Units
PubMed
Doi

Citation
Dummer R, Cozzio A, Urosevic M. Pathogenesis and therapy of cutaneous lymphomas--progress or impasse?. Exp Dermatol 2006; 15:392-400.
Type
Journal Paper/Review (English)
Journal
Exp Dermatol 2006; 15
Publication Date
May 1, 2006
Issn Print
0906-6705
Pages
392-400
Brief description/objective

The cutaneous environment hosts a number of hematopoietic neoplasms that are dominated by primary cutaneous (PC) T-cell lymphomas. Recent progress in molecular biology and immunology has provided tools to investigate the pathogenesis and the biology of these neoplasms. This review highlights newest findings concerning the immune biology of CD4+ CD56+ hematodermic neoplasms, and PC T-cell and B-cell lymphomas, speculating how these can be translated into more sophisticated, biology-based treatment approaches in the near future.