In vivo detection of metastatic ovarian cancer by means of 5-aminolevulinic acid-induced fluorescence in a rat model

Publication

In vivo detection of metastatic ovarian cancer by means of 5-aminolevulinic acid-induced fluorescence in a rat model

Journal Paper/Review - May 2, 1998

Hornung René, Major Atilla L., McHale Michael, Liaw Lih-Huei L., Sabiniano Leslie A., Tromberg Bruce J., W. Berns Michael, Tadir Yona

Citation

Hornung R, Major A, McHale M, Liaw L, Sabiniano L, Tromberg B, W. Berns M, Tadir Y. In vivo detection of metastatic ovarian cancer by means of 5-aminolevulinic acid-induced fluorescence in a rat model. J am Assoc Gynecol Laparosc. 1998; 5:141-148.

Type

Journal Paper/Review (English)

Journal

J am Assoc Gynecol Laparosc. 1998; 5

Publication Date

May 2, 1998

Pages

141-148

Publisher

Elsevier Inc. (Philadephia (USA))

Brief description/objective

To determine the feasibility of macroscopic visualization of small ovarian cancer metastases in vivo by fluorescence after intravenous administration of 5-aminolevulinic acid (ALA); to assess the time after drug injection when fluorescence of small metastases is maximum; and to correlate macroscopic in vivo fluorescence with both microscopic ex vivo fluorescence and histologic findings.