Selective axillary surgery in breast cancer patients based on positron emission tomography with 18F-fluoro-2-deoxy-D-glucose: not yet!

Publication

Selective axillary surgery in breast cancer patients based on positron emission tomography with 18F-fluoro-2-deoxy-D-glucose: not yet!

Journal Paper/Review - Jan 1, 2002

Gueller Ulrich, Harder Felix, Oertli Daniel, Marti Walter R, Langer Igor, Moch Holger, Torhorst Joachim, Viehl Carsten T, Schirp Udo, Nitzsche Egbert U, Zuber Markus

Units

Medizinische Onkologie und Hämatologie

PubMed

11881913

Citation

Gueller U, Harder F, Oertli D, Marti W, Langer I, Moch H, Torhorst J, Viehl C, Schirp U, Nitzsche E, Zuber M. Selective axillary surgery in breast cancer patients based on positron emission tomography with 18F-fluoro-2-deoxy-D-glucose: not yet!. Breast Cancer Res Treat 2002; 71:171-3.

Type

Journal Paper/Review (English)

Journal

Breast Cancer Res Treat 2002; 71

Publication Date

Jan 1, 2002

Issn Print

0167-6806

Pages

171-3

Brief description/objective

We prospectively evaluated 31 patients with invasive breast cancer. Preoperative positron emission tomography (PET) with 18F-fluoro-2-deoxy-D-glucose (18F-FDG) for detection of axillary lymph node metastases was compared with the histopathologic status of the sentinel lymph node (SLN). Sensitivity of PET imaging was 43%, specificity and negative predictive value were 94 and 67%, respectively. The smallest metastasis detected by PET measured 3 mm in diameter. The results of this study suggest that detection of small axillary lymph node metastases is limited by the currently achievable spatial resolution of PET imaging. Selective axillary surgery in breast cancer patients based on 18F-FDG PET is yet not possible.