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Bacillary Angiomatosis and Bacteremia due to Bartonella quintana in a Patient with Chronic Lymphocytic Leukemia

Journal Paper/Review - Apr 28, 2013

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Citation
Fulchini R, Bloemberg G, Boggian K. Bacillary Angiomatosis and Bacteremia due to Bartonella quintana in a Patient with Chronic Lymphocytic Leukemia. Case Rep Infect Dis 2013; 2013:694765.
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Journal Paper/Review (English)
Journal
Case Rep Infect Dis 2013; 2013
Publication Date
Apr 28, 2013
Issn Print
2090-6625
Issn Electronic
Pages
694765
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Brief description/objective

We present a 63-year-old man treated with alemtuzumab for chronic lymphocytic leukemia who developed multiple angiomatous papules and fever. Real-time polymerase chain reaction (RT-PCR) from a skin lesion and blood sample revealed Bartonella quintana as causative agent confirming the diagnosis of bacillary angiomatosis with bacteremia. Treatment with doxycycline, initially in combination with gentamicin, led to complete resolution of the lesions. This case shows the importance of considering bacillary angiomatosis as a rare differential diagnosis of angiomatous lesions in the immunocompromised patient, particularly in chronic lymphocytic leukemia and following lymphocyte depleting treatments as alemtuzumab.