The immune system in the pathogenesis of vascular disease

Publication

The immune system in the pathogenesis of vascular disease

Book Chapter - Jan 1, 2007

Ludewig Burkhard, Laman Jon D.

Units

Medizinisches Forschungszentrum, Institute of Immunobiology

Keywords

Myocarditis, Vasculitis

Doi

10.1007/978-1-59745-001-0

Citation

Ludewig B, Laman J. The immune system in the pathogenesis of vascular disease. In: Essentials of restenosis for the interventional cardiologist. Totowa, New Jersey: Humana Press, 2007. ISBN 978-1-58829-491-3. pp. 85-130.

Type

Book Chapter (Deutsch)

Book Title

Essentials of restenosis for the interventional cardiologist

Publication Date

Jan 1, 2007

Series Title

Contemporary Cardiology ()

Isbn Number

978-1-58829-491-3

Pages

85-130

Publisher

Humana Press (Totowa, New Jersey)

Brief description/objective

During the recent years, cardiovascular and immunological research has provided profound experimental and clinical evidence supporting the notion that inflammation and immune responses are crucial components of vascular proliferative diseases. This chapter aims to provide a state of the art overview of this concept. In doing so, we discuss a number of novel developments in the highly dynamic field of immunology, with particular emphasis on their relevance for cardiovascular disease. These include functional subsets of macrophages and T lymphocytes, newly identified receptors for pathogens, the reciprocal regulation of lipid metabolism, inflammation and infection, and the hygiene hypothesis.