Down regulation of E-Cadherin (ECAD) - a predictor for occult metastatic disease in sentinel node biopsy of early squamous cell carcinomas of the oral cavity and oropharynx - Publication

Publication

Down regulation of E-Cadherin (ECAD) - a predictor for occult metastatic disease in sentinel node biopsy of early squamous cell carcinomas of the oral cavity and oropharynx

Journal Paper/Review - Jun 3, 2011

Huber Gerhard F, Züllig Lena, Soltermann Alex, Roessle Matthias, Haerle Stephan K, Studer Gabriela, Jochum Wolfram, Moch Holger, Stöckli Sandro

Citation

Huber G, Züllig L, Soltermann A, Roessle M, Haerle S, Studer G, Jochum W, Moch H, Stöckli S. Down regulation of E-Cadherin (ECAD) - a predictor for occult metastatic disease in sentinel node biopsy of early squamous cell carcinomas of the oral cavity and oropharynx. BMC cancer 2011; 11:217:1-8.

Type

Journal Paper/Review (English)

Journal

BMC cancer 2011; 11

Publication Date

Jun 3, 2011

Issn Electronic

1471-2407

Pages

217:1-8

Brief description/objective

Prognostic factors in predicting occult lymph node metastasis in patients with head and neck squamous-cell carcinoma (HNSCC) are necessary to improve the results of the sentinel lymph node procedure in this tumour type. The E-Cadherin glycoprotein is an intercellular adhesion molecule in epithelial cells, which plays an important role in establishing and maintaining intercellular connections.