Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice

Publication

Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice

Journal Paper/Review - Feb 1, 2004

Redaelli Claudio A, Semela David, Carrick Francine E, Ledermann Monika, Candinas Daniel, Sauter Bernhard, Dufour Jean-François

Units

Gastroenterology/Hepatology

PubMed

14739103

Citation

Redaelli C, Semela D, Carrick F, Ledermann M, Candinas D, Sauter B, Dufour J. Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice. J Hepatol 2004; 40:305-12.

Type

Journal Paper/Review (English)

Journal

J Hepatol 2004; 40

Publication Date

Feb 1, 2004

Issn Print

0168-8278

Pages

305-12

Brief description/objective

Liver regeneration is dependent upon coordinated proliferation of hepatocytes and endothelial cells. Vascular endothelial growth factor (VEGF) promotes angiogenesis. Hepatic steatosis delays regeneration and increases liver resection morbidity. We hypothesized that VEGF overexpression stimulates hepatic regeneration.