Publication

Contact dermatitis induced by glatiramer acetate

Journal Paper/Review - Jul 5, 2011

Units
PubMed
Doi

Citation
Haltmeier S, Yildiz M, Müller S, Anliker M, Heinzerling L. Contact dermatitis induced by glatiramer acetate. Mult Scler 2011; 17:1390-2.
Type
Journal Paper/Review (English)
Journal
Mult Scler 2011; 17
Publication Date
Jul 5, 2011
Issn Electronic
1477-0970
Pages
1390-2
Brief description/objective

Glatiramer acetate (Copaxone(®)) is an immunomodulatory polypeptide used in patients with relapsing-remitting multiple sclerosis. It represents a safe treatment option with mild side effects. In this study, we look at a 39-year-old woman who received glatiramer acetate as subcutaneous injections for two months and developed contact dermatitis. The drug had to be stopped, and treatment with topical prednisone was initiated. Prick/scratch testing was negative but the lymphocyte transformation test was highly positive for glatiramer acetate. This is the first report on contact dermatitis induced by glatiramer acetate injections. The treatment consisted of local topical steroids and cessation of the drug.