Preexposure prophylaxis and timed intercourse for HIV-discordant couples willing to conceive a child

Publication

Preexposure prophylaxis and timed intercourse for HIV-discordant couples willing to conceive a child

Journal Paper/Review - Oct 23, 2011

Vernazza Pietro, Graf Irma, Sonnenberg-Schwan Ulrike, Geit Maria, Meurer Anja

Citation

Vernazza P, Graf I, Sonnenberg-Schwan U, Geit M, Meurer A. Preexposure prophylaxis and timed intercourse for HIV-discordant couples willing to conceive a child. AIDS 2011; 25:2005-8.

Type

Journal Paper/Review (English)

Journal

AIDS 2011; 25

Publication Date

Oct 23, 2011

Issn Electronic

1473-5571

Pages

2005-8

Brief description/objective

Many HIV-discordant couples express a strong wish to conceive a child. Insemination with processed semen is offered to these couples in many countries. Given the very low level of transmission risk during fully suppressive antiretroviral therapy, we offered timed intercourse combined with preexposure prophylaxis to further reduce the transmission risk. In 53 cases, natural conception was attempted using the proposed method. Pregnancy rates were high and reached a plateau of 75% after six cycles. Advanced age in the female partner was a predictor for infertility in these couples.