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Infrequent detection of lipoarabinomannan antibodies in human immunodeficiency virus-associated mycobacterial disease. Swiss HIV Cohort Study

Journal Paper/Review - Jul 1, 1996

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Citation
Boggian K, Fierz W, Vernazza P. Infrequent detection of lipoarabinomannan antibodies in human immunodeficiency virus-associated mycobacterial disease. Swiss HIV Cohort Study. J Clin Microbiol 1996; 34:1854-5.
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Journal Paper/Review (English)
Journal
J Clin Microbiol 1996; 34
Publication Date
Jul 1, 1996
Issn Print
0095-1137
Issn Electronic
Pages
1854-5
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Brief description/objective

A commercially available test for the serologic diagnosis of tuberculosis was evaluated for its applicability in human immunodeficiency virus (HIV)-positive patients. Antibodies to lipoarabinomannan were detectable in sera from only 9 of 85 HIV-positive patients with a confirmed diagnosis of tuberculosis. Given the low degree of sensitivity of the assay with sera from HIV-infected patients, the study does not support the use of this serologic assay for the diagnosis of tuberculosis in HIV-infected patients.