Infrequent detection of lipoarabinomannan antibodies in human immunodeficiency virus-associated mycobacterial disease. Swiss HIV Cohort Study

Publication

Infrequent detection of lipoarabinomannan antibodies in human immunodeficiency virus-associated mycobacterial disease. Swiss HIV Cohort Study

Journal Paper/Review - Jul 1, 1996

Boggian Katia, Fierz W, Vernazza P L

Units

Division of Infectious Diseases, Infection Prevention and Travel Medicine

PubMed

8784611

Citation

Boggian K, Fierz W, Vernazza P. Infrequent detection of lipoarabinomannan antibodies in human immunodeficiency virus-associated mycobacterial disease. Swiss HIV Cohort Study. J Clin Microbiol 1996; 34:1854-5.

Type

Journal Paper/Review (English)

Journal

J Clin Microbiol 1996; 34

Publication Date

Jul 1, 1996

Issn Print

0095-1137

Pages

1854-5

Brief description/objective

A commercially available test for the serologic diagnosis of tuberculosis was evaluated for its applicability in human immunodeficiency virus (HIV)-positive patients. Antibodies to lipoarabinomannan were detectable in sera from only 9 of 85 HIV-positive patients with a confirmed diagnosis of tuberculosis. Given the low degree of sensitivity of the assay with sera from HIV-infected patients, the study does not support the use of this serologic assay for the diagnosis of tuberculosis in HIV-infected patients.