Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia

Publication

Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia

Journal Paper/Review - Apr 1, 2004

Vavricka S R, Halter J, Hechelhammer Lukas, Himmelmann A

Units

Radiologie und Nuklearmedizin

PubMed

15082848

Citation

Vavricka S, Halter J, Hechelhammer L, Himmelmann A. Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia. Postgrad Med J 2004; 80:236-8.

Type

Journal Paper/Review (English)

Journal

Postgrad Med J 2004; 80

Publication Date

Apr 1, 2004

Issn Print

0032-5473

Pages

236-8

Brief description/objective

Pneumocystis carinii pneumonia in patients with chronic lymphocytic leukaemia (CLL) who have not been treated with fludarabin are rare, although clinically relevant CD4 T-cell depletion can occur in longstanding CLL without prior treatment with purine analogues. A 52 year old woman is reported who was on long term treatment with chlorambucil and taking a short course of prednisone for familial CLL before she developed progressive dyspnoea, and P carinii pneumonia was diagnosed in bronchoalveolar lavage fluid. Despite treatment with high dose co-trimoxazole the patient died.