Publication

GD1a-associated pure motor Guillain-Barré syndrome with hyperreflexia and bilateral papillitis

Journal Paper/Review - Mar 1, 2010

Units
PubMed
Doi

Citation
Neuwirth C, Mojon D, Weber M. GD1a-associated pure motor Guillain-Barré syndrome with hyperreflexia and bilateral papillitis. J Clin Neuromuscul Dis 2010; 11:114-9.
Type
Journal Paper/Review (English)
Journal
J Clin Neuromuscul Dis 2010; 11
Publication Date
Mar 1, 2010
Issn Electronic
1537-1611
Pages
114-9
Brief description/objective

A patient with acute purely motor polyneuropathy with positive GD1a ganglioside antibodies who presented with paresis in combination with hyperreflexia is reported. Neurophysiological tests revealed features compatible with acute motor axonal neuropathy. Therapy with intravenous immunoglobulin led to rapid clinical improvement. However, at the time when signs of active denervation appeared on electromyographic testing, the patient developed bilateral papillitis. The pathogenesis of pure motor Guillain-Barré syndrome with hyperreflexia and papillitis is discussed.