[Seizure and non-cardiogenic pulmonary edema after intoxication]

Publication

[Seizure and non-cardiogenic pulmonary edema after intoxication]

Journal Paper/Review - Apr 1, 2010

Sawatzki Mikael, Kummer O, Krähenbühl S, Siegemund M

Citation

Sawatzki M, Kummer O, Krähenbühl S, Siegemund M. [Seizure and non-cardiogenic pulmonary edema after intoxication]. Internist (Berl) 2010; 51:528-32.

Type

Journal Paper/Review (Deutsch)

Journal

Internist (Berl) 2010; 51

Publication Date

Apr 1, 2010

Issn Electronic

1432-1289

Pages

528-32

Brief description/objective

We report a case of severe intoxication with extended-release verapamil. In addition to cardiovascular toxicities with hypotension, atrioventricular block and bradycardia, the patient suffered from grand-mal seizure and pulmonary edema 13 and 48 hours respectively, after ingestion of 4.8 g of extended-release verapamil. Adverse reactions after intoxications with extended-release tablets appear delayed with prolonged manifestation of symptoms. Early and repetitive administration of activated charcoal and antegrade whole bowel lavage are crucial, even in primary asymptomatic patients.