Functional genomics and gene microarrays--the use in research and clinical medicine

Publication

Functional genomics and gene microarrays--the use in research and clinical medicine

Journal Paper/Review - Jan 25, 2003

Joos Ladina, Eryüksel Emel, Brutsche Martin

Citation

Joos L, Eryüksel E, Brutsche M. Functional genomics and gene microarrays--the use in research and clinical medicine. Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology 2003; 133:31-8.

Type

Journal Paper/Review (English)

Journal

Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology 2003; 133

Publication Date

Jan 25, 2003

Issn Print

1424-7860

Pages

31-8

Brief description/objective

In the year 2000, the Human Genome Project Consortium presented the first complete draft of the human genome together with Celera Genetics. Since then, the so-called "post-genome era" has started. Microarrays are capable of profiling gene expression patterns of tens of thousands of genes in a single experiment and thus allow a systematic analysis of DNA and RNA variation. They seem likely to become a standard tool of both molecular biology research and clinical diagnostics. These prospects have attracted great interest and investment from both the public and private sectors. This review introduces the principle of microarray technology and gives an overview of its current and future potential in clinical medicine.