Unusually high HIV infectiousness in an HIV-, HCV- and HSV-2-coinfected heterosexual man

Publication

Unusually high HIV infectiousness in an HIV-, HCV- and HSV-2-coinfected heterosexual man

Journal Paper/Review - Apr 4, 2009

Witteck Andrea, Yerly Sabine, Vernazza Pietro

Citation

Witteck A, Yerly S, Vernazza P. Unusually high HIV infectiousness in an HIV-, HCV- and HSV-2-coinfected heterosexual man. Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology 2009; 139:207-9.

Type

Journal Paper/Review (English)

Journal

Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology 2009; 139

Publication Date

Apr 4, 2009

Issn Print

1424-7860

Pages

207-9

Brief description/objective

We report an HIV-HCV-HSV-2-coinfected man, who infected all of five sequential female sexual partners within seven years. HIV-RNA in semen was unusually high and exceeded that in plasma by one log10. Screening for sexually transmitted diseases remained negative with the exception of HSV-2-seropositivity. Recurrent asymptomatic genital herpes might explain the patient's increased HIV-RNA shedding in semen.