Bland-White-Garland syndrome and atrial septal defect - rare association and diagnostic challenge - Publication

Publication

Bland-White-Garland syndrome and atrial septal defect - rare association and diagnostic challenge

Journal Paper/Review - May 1, 2006

Schneider T, Rickli Hans, Gliech V, Maeder Micha

Citation

Schneider T, Rickli H, Gliech V, Maeder M. Bland-White-Garland syndrome and atrial septal defect - rare association and diagnostic challenge. Clinical research in cardiology : official journal of the German Cardiac Society 2006; 95:295-300.

Type

Journal Paper/Review (English)

Journal

Clinical research in cardiology : official journal of the German Cardiac Society 2006; 95

Publication Date

May 1, 2006

Issn Print

1861-0684

Pages

295-300

Brief description/objective

We report on a 40-year-old woman referred for evaluation of a cardiac murmur and dyspnea on exertion. The electrocardiogram (ECG) showed incomplete right bundle branch block, and echocardiography revealed a large atrial septal defect (ASD, ostium secundum type) with dilated right-sided heart chambers. At cardiac catheterization, a large left-to-right shunt (78% of the pulmonary blood flow) was found, and surprisingly, the additional diagnosis of anomalous origin of the left coronary artery from pulmonary artery (ALCAPA) was established. After ASD closure and left coronary artery ligation with implantation of a vein graft to the left anterior descending artery, she had an uneventful 18-years follow-up. We discuss the interaction of the two associated conditions, and based on the herein reported unusual combination, we highlight typical features of non-invasive examinations including auscultation, ECG, and echocardiography in adult patients with ALCAPA.