Publication

Secondary adrenal insufficiency due to opiate therapy - another differential diagnosis worth consideration

Journal Paper/Review - Nov 1, 2009

Units
PubMed
Doi

Citation
Schimke K, Greminger P, Brändle M. Secondary adrenal insufficiency due to opiate therapy - another differential diagnosis worth consideration. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009; 117:649-51.
Type
Journal Paper/Review (English)
Journal
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009; 117
Publication Date
Nov 1, 2009
Issn Electronic
1439-3646
Pages
649-51
Brief description/objective

We report on a 64-year-old patient in whom fentanyl therapy was found to be responsible for the induction of secondary adrenal insufficiency as clearly demonstrated by re-exposure. We conclude that given the widespread use of opiates in chronic pain management physicians should raise their level of awareness for adrenal insufficiency and look for it generously. Opiates should be added to the list of differential diagnoses to be considered routinely in patients with newly diagnosed secondary adrenal insufficiency.