Publication
Pre-transplant donor specific antibodies in ABO incompatible kidney transplantation - data from the Swiss transplant cohort study.
Journal Paper/Review - Feb 1, 2024
Deng Yun, Frischnknecht Lukas, Wehmeier Caroline, de Rougemont Olivier, Villard Jean, Ferrari-Lacraz Sylvie, Golshayan Délaviz, Gannagé Monique, Binet Françoise-Isabelle, Wirthmueller Urs, Sidler Daniel, Schachtner Thomas, Schaub Stefan, Nilsson Jakob
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Brief description/objective
Living donor (LD) kidney transplantation in the setting of ABO blood group incompatibility (ABOi) has been previously reported to be associated with increased risk for antibody-mediated rejection (ABMR). It is however unclear if the presence of pre-transplant donor specific antibodies (DSA) works as an additive risk factor in the setting of ABOi and if DSA positive ABOi transplants have a significantly worse long-term outcome as compared with ABO compatible (ABOc) DSA positive transplants.