Publication

Pre-transplant donor specific antibodies in ABO incompatible kidney transplantation - data from the Swiss transplant cohort study.

Journal Paper/Review - Feb 1, 2024

Units
PubMed
Doi
Contact

Citation
Deng Y, Frischnknecht L, Wehmeier C, de Rougemont O, Villard J, Ferrari-Lacraz S, Golshayan D, Gannagé M, Binet F, Wirthmueller U, Sidler D, Schachtner T, Schaub S, Nilsson J. Pre-transplant donor specific antibodies in ABO incompatible kidney transplantation - data from the Swiss transplant cohort study. Front Immunol 2024; 15:1355128.
Type
Journal Paper/Review (English)
Journal
Front Immunol 2024; 15
Publication Date
Feb 1, 2024
Issn Electronic
1664-3224
Pages
1355128
Brief description/objective

Living donor (LD) kidney transplantation in the setting of ABO blood group incompatibility (ABOi) has been previously reported to be associated with increased risk for antibody-mediated rejection (ABMR). It is however unclear if the presence of pre-transplant donor specific antibodies (DSA) works as an additive risk factor in the setting of ABOi and if DSA positive ABOi transplants have a significantly worse long-term outcome as compared with ABO compatible (ABOc) DSA positive transplants.