The Vitamin D Metabolite Diagnostic Ratio Associates With Phenotypic Traits of Idiopathic Hypercalciuria.

Publication

The Vitamin D Metabolite Diagnostic Ratio Associates With Phenotypic Traits of Idiopathic Hypercalciuria.

Journal Paper/Review - Jan 10, 2024

Dhayat Nasser A, Mattmann Cédric, Seeger Harald, Ritter Alexander, Ernandez Thomas, Stoermann-Chopard Catherine, Buchkremer Florian, Segerer Stephan, Roth Beat, Wuerzner Gregoire, Wagner Carsten A, Bonny Olivier, Popp Albrecht W, Vogt Bruno, Bargagli Matteo, Fuster Daniel G

Citation

Dhayat N, Mattmann C, Seeger H, Ritter A, Ernandez T, Stoermann-Chopard C, Buchkremer F, Segerer S, Roth B, Wuerzner G, Wagner C, Bonny O, Popp A, Vogt B, Bargagli M, Fuster D. The Vitamin D Metabolite Diagnostic Ratio Associates With Phenotypic Traits of Idiopathic Hypercalciuria. Kidney Int Rep 2024; 9:1072-1082.

Type

Journal Paper/Review (English)

Journal

Kidney Int Rep 2024; 9

Publication Date

Jan 10, 2024

Issn Electronic

2468-0249

Pages

1072-1082

Brief description/objective

Underlying mechanisms for hypercalciuria remain unknown in most cases; thus, the designation "idiopathic." We hypothesized that the vitamin D-inactivating enzyme, CYP24A1 contributes to the pathogenesis of hypercalciuria in kidney stone formers.