Cluster Analysis to Explore Clinical Subphenotypes of Eosinophilic Granulomatosis With Polyangiitis.

Publication

Cluster Analysis to Explore Clinical Subphenotypes of Eosinophilic Granulomatosis With Polyangiitis.

Journal Paper/Review - Sep 22, 2023

Rubenstein Emma, Maldini Carla Soledad, Vaglio Augusto, Bello Federica, Bremer Jan Phillip, Moosig Frank, Bottero Paolo, Pesci Alberto, Sinico Renato Alberto, Grosskreutz Julian, Feder Claudia, Saadoun David, Trivioli Giorgio, Maritati Federica, Rewerska Barbara, Szczeklik Wojciech, Fraticelli Paolo, Guida Giuseppe, Gregorini Gina, Moroncini Gianluca, Hellmich Bernhard, Zwerina Jochen, Resche-Rigon Matthieu, Emmi Giacomo, Neumann Thomas, Mahr Alfred

Citation

Rubenstein E, Maldini C, Vaglio A, Bello F, Bremer J, Moosig F, Bottero P, Pesci A, Sinico R, Grosskreutz J, Feder C, Saadoun D, Trivioli G, Maritati F, Rewerska B, Szczeklik W, Fraticelli P, Guida G, Gregorini G, Moroncini G, Hellmich B, Zwerina J, Resche-Rigon M, Emmi G, Neumann T, Mahr A. Cluster Analysis to Explore Clinical Subphenotypes of Eosinophilic Granulomatosis With Polyangiitis. J Rheumatol 2023; 50:1446-1453.

Type

Journal Paper/Review (English)

Journal

J Rheumatol 2023; 50

Publication Date

Sep 22, 2023

Issn Electronic

1499-2752

Pages

1446-1453

Brief description/objective

Previous studies suggested that distinct phenotypes of eosinophilic granulomatosis with polyangiitis (EGPA; formerly known as Churg-Strauss syndrome) could be determined by the presence or absence of antineutrophil cytoplasmic antibodies (ANCA), reflecting predominant vasculitic or eosinophilic processes, respectively. This study explored whether ANCA-based clusters or other clusters can be identified in EGPA.