Efficacy, safety, and prognosis prediction in patients treated with ribociclib in combination with letrozole: Final results of phase 3b RIBECCA study in hormone receptor positive, human epidermal growth factor receptor-2 negative, locally advanced or metastatic breast cancer.

Publication

Efficacy, safety, and prognosis prediction in patients treated with ribociclib in combination with letrozole: Final results of phase 3b RIBECCA study in hormone receptor positive, human epidermal growth factor receptor-2 negative, locally advanced or metastatic breast cancer.

Journal Paper/Review - Dec 15, 2023

Fasching Peter Andreas, Decker Thomas, Hartkopf Andreas D, Nusch Arnd, Heinrich Bernhard J, Kurbacher Christian M, Fuchs Roswitha, Tesch Hans, Krabisch Petra, Huober Jens, Kümmel Sherko, Brucker Sara Y, Janni Wolfgang, Schneeweiss Andreas, Schuler Martin, Fehm Tanja N, Luftner Diana, Quiering Claudia, Voges Claudia, Kreuzeder Julia, Reinisch Mattea

Citation

Fasching P, Decker T, Hartkopf A, Nusch A, Heinrich B, Kurbacher C, Fuchs R, Tesch H, Krabisch P, Huober J, Kümmel S, Brucker S, Janni W, Schneeweiss A, Schuler M, Fehm T, Luftner D, Quiering C, Voges C, Kreuzeder J, Reinisch M. Efficacy, safety, and prognosis prediction in patients treated with ribociclib in combination with letrozole: Final results of phase 3b RIBECCA study in hormone receptor positive, human epidermal growth factor receptor-2 negative, locally advanced or metastatic breast cancer. Eur J Cancer 2023; 198:113480.

Type

Journal Paper/Review (English)

Journal

Eur J Cancer 2023; 198

Publication Date

Dec 15, 2023

Issn Electronic

1879-0852

Pages

113480

Brief description/objective

In MONALEESA-2, addition of ribociclib to letrozole resulted in significantly longer progression-free survival (PFS) in postmenopausal women with HR+HER2- advanced breast cancer (ABC). RIBociclib for the treatment of advanCed breast CAncer (RIBECCA) study investigated ribociclib plus letrozole in a patient population reflecting routine clinical practice.