Minimally Invasive Breast Biopsy After Neoadjuvant Systemic Treatment to Identify Breast Cancer Patients with Residual Disease for Extended Neoadjuvant Treatment: A New Concept.

Publication

Minimally Invasive Breast Biopsy After Neoadjuvant Systemic Treatment to Identify Breast Cancer Patients with Residual Disease for Extended Neoadjuvant Treatment: A New Concept.

Journal Paper/Review - Nov 10, 2023

Pfob André, Cai Lie, Schneeweiss Andreas, Rauch Geraldine, Thomas Bettina, Schaefgen Benedikt, Kümmel Sherko, Reimer Toralf, Hahn Markus, Thill Marc, Blohmer Jens-Uwe, Hackmann John, Malter Wolfram, Bekes Inga, Friedrichs Kay, Wojcinski Sebastian, Joos Sylvie, Paepke Stefan, Degenhardt Tom, Rom Joachim, Rody Achim, van Mackelenbergh Marion T, Banys-Paluchowski Maggie, Große Regina, Reinisch Mattea, Karsten Maria Margarete, Sidey-Gibbons Chris, Wallwiener Markus, Golatta Michael, Heil Jörg

Citation

Pfob A, Cai L, Schneeweiss A, Rauch G, Thomas B, Schaefgen B, Kümmel S, Reimer T, Hahn M, Thill M, Blohmer J, Hackmann J, Malter W, Bekes I, Friedrichs K, Wojcinski S, Joos S, Paepke S, Degenhardt T, Rom J, Rody A, van Mackelenbergh M, Banys-Paluchowski M, Große R, Reinisch M, Karsten M, Sidey-Gibbons C, Wallwiener M, Golatta M, Heil J. Minimally Invasive Breast Biopsy After Neoadjuvant Systemic Treatment to Identify Breast Cancer Patients with Residual Disease for Extended Neoadjuvant Treatment: A New Concept. Ann Surg Oncol 2023

Type

Journal Paper/Review (English)

Journal

Ann Surg Oncol 2023

Publication Date

Nov 10, 2023

Issn Electronic

1534-4681

Brief description/objective

Breast cancer patients with residual disease after neoadjuvant systemic treatment (NAST) have a worse prognosis compared with those achieving a pathologic complete response (pCR). Earlier identification of these patients might allow timely, extended neoadjuvant treatment strategies. We explored the feasibility of a vacuum-assisted biopsy (VAB) after NAST to identify patients with residual disease (ypT+ or ypN+) prior to surgery.