Nonconvulsive seizures in subarachnoid hemorrhage link inflammation and outcome.

Publication

Nonconvulsive seizures in subarachnoid hemorrhage link inflammation and outcome.

Journal Paper/Review - May 16, 2014

Claassen Jan, Albers David, Sanchez Schmidt J M, De Marchis Gian Marco, Pugin Deborah, Falo Christina Maria, Mayer Stephan A, Cremers Serge, Agarwal Sachin, Elkind Mitchell S V, Connolly E Sander, Dukic Vanja, Hripcsak George, Badjatia Neeraj

Citation

Claassen J, Albers D, Sanchez Schmidt J, De Marchis G, Pugin D, Falo C, Mayer S, Cremers S, Agarwal S, Elkind M, Connolly E, Dukic V, Hripcsak G, Badjatia N. Nonconvulsive seizures in subarachnoid hemorrhage link inflammation and outcome. Ann Neurol 2014; 75:771-81.

Type

Journal Paper/Review (English)

Journal

Ann Neurol 2014; 75

Publication Date

May 16, 2014

Issn Electronic

1531-8249

Pages

771-81

Brief description/objective

Nonconvulsive seizures (NCSz) are frequent following acute brain injury and have been implicated as a cause of secondary brain injury, but mechanisms that cause NCSz are controversial. Proinflammatory states are common after many brain injuries, and inflammation-mediated changes in blood-brain barrier permeability have been experimentally linked to seizures.