Donation type and the effect of pre-transplant donor specific antibodies - Data from the Swiss Transplant Cohort Study.
Journal Paper/Review - Feb 15, 2023
de Rougemont Olivier, Deng Yun, Frischknecht Lukas, Wehmeier Caroline, Villard Jean, Ferrari-Lacraz Sylvie, Golshayan Déla, Gannagé Monique, Binet Isabelle, Wirthmueller Urs, Sidler Daniel, Schachtner Thomas, Schaub Stefan, Nilsson Jakob, Swiss Transplant Cohort Study
The type of donation may affect how susceptible a donor kidney is to injury from pre-existing alloimmunity. Many centers are, therefore, reluctant to perform donor specific antibody (DSA) positive transplantations in the setting of donation after circulatory death (DCD). There are, however, no large studies comparing the impact of pre-transplant DSA stratified on donation type in a cohort with a complete virtual cross-match and long-term follow-up of transplant outcome.