Laser Interstitial Thermal Therapy for Radionecrosis.

Publication

Laser Interstitial Thermal Therapy for Radionecrosis.

Journal Paper/Review - Jan 31, 2023

Terrapon Alexis Paul Romain, Krüger Marie Therese, Hundsberger Thomas, Neidert Marian Christoph, Bozinov Oliver

Citation

Terrapon A, Krüger M, Hundsberger T, Neidert M, Bozinov O. Laser Interstitial Thermal Therapy for Radionecrosis. Neurosurg Clin N Am 2023; 34:209-225.

Type

Journal Paper/Review (English)

Journal

Neurosurg Clin N Am 2023; 34

Publication Date

Jan 31, 2023

Issn Electronic

1558-1349

Pages

209-225

Brief description/objective

Radiotherapy is widely used for brain tumors but can cause radiation necrosis (RN). Laser interstitial thermal therapy (LITT) is a relatively new therapeutic modality for RN and its impact on patient outcome is still not well understood. Based on a systematic literature search (n=33), the authors discuss the available evidence. Most studies found a positive safety/efficacy profile, as LITT may help to lengthen survival, prevent progression, taper steroids, and improve neurological symptoms while remaining safe. Prospective studies on this subject are needed and may result in LITT becoming an essential therapeutic option for the treatment of RN.