Impact of Latent Tuberculosis on Diabetes.

Publication

Impact of Latent Tuberculosis on Diabetes.

Journal Paper/Review - Jun 15, 2022

Tepekule Burcu, Kusejko Katharina, Zeeb Marius, Tarr Philip E, Calmy Alexandra, Battegay Manuel, Furrer Hansjakob, Cavassini Matthias, Bernasconi Enos, Notter Julia, Günthard Huldrych F, Nemeth Johannes, Kouyos Roger D, Swiss HIV Cohort Study

Citation

Tepekule B, Kusejko K, Zeeb M, Tarr P, Calmy A, Battegay M, Furrer H, Cavassini M, Bernasconi E, Notter J, Günthard H, Nemeth J, Kouyos R, Swiss HIV Cohort Study. Impact of Latent Tuberculosis on Diabetes. J Infect Dis 2022; 225:2229-2234.

Type

Journal Paper/Review (English)

Journal

J Infect Dis 2022; 225

Publication Date

Jun 15, 2022

Issn Electronic

1537-6613

Pages

2229-2234

Brief description/objective

While an increased risk of active and latent tuberculosis infection (LTBI) in people with type-2 diabetes (DM) has been demonstrated, it is less well characterized whether LTBI is associated with an increased risk of developing DM. We investigated the link between LTBI and DM in people living with HIV in the Swiss HIV Cohort Study via time-dependent Cox proportional hazards models. We found that LTBI significantly increased the risk of developing DM (HR = 1.47), which was robust across different adjustment and censoring techniques. Our results thus suggest that LTBI may be associated with an increased risk of developing DM.