C-reactive protein elevation predicts in-hospital deterioration after aneurysmal subarachnoid hemorrhage: a retrospective observational study.

Publication

C-reactive protein elevation predicts in-hospital deterioration after aneurysmal subarachnoid hemorrhage: a retrospective observational study.

Journal Paper/Review - May 26, 2022

Alessandro Ostini, Warschkow Rene, Stefan Wolf, Filipovic Miodrag, Seule Martin, Bozinov Oliver, Pietsch Urs

Citation

Alessandro O, Warschkow R, Stefan W, Filipovic M, Seule M, Bozinov O, Pietsch U. C-reactive protein elevation predicts in-hospital deterioration after aneurysmal subarachnoid hemorrhage: a retrospective observational study. Acta Neurochir (Wien) 2022; 164:1805-1814.

Type

Journal Paper/Review (English)

Journal

Acta Neurochir (Wien) 2022; 164

Publication Date

May 26, 2022

Issn Electronic

0942-0940

Pages

1805-1814

Brief description/objective

There is increasing evidence that inflammation plays a role in the pathogenesis of aneurysmal subarachnoid hemorrhage (aSAH) and in the development of delayed cerebral ischemia (DCI). However, the assessment and interpretation of classically defined inflammatory parameters is difficult in aSAH patients. The objective of this study was to investigate the relationship between easily assessable findings (hyperventilation, fever, white blood cell count (WBC), and C-reactive protein (CRP)) and the occurrence of DCI and unfavorable neurological outcome at discharge in aSAH patients.